EC Number   |
Protein Variants |
Reference |
|---|
   2.4.1.41 | AA93-563 |
abbreviated as sGalntl-1, N-terminal transmembrane domain replaced by the Chordin N-terminal leader peptide followed by Flag-tag, no enhanced secretion compared to wild-type, altered activity in Xenopus embryo, no interference with binding of ActRII-B to type I TGFbeta receptor proteins |
686299 |
| 2.4.1.41 | C479F |
naturally occuring mutation |
706506 |
| 2.4.1.41 | D155N |
ppGaNTase-T1 mutant with wild type level of enzyme activity, expression in COS7 cells is markedly compromised |
489189 |
| 2.4.1.41 | D156Q |
ppGaNTase-T1 mutant without enzyme activity |
489189 |
| 2.4.1.41 | D209A |
inactive mutant enzyme |
660415 |
| 2.4.1.41 | D209A |
ppGaNTase-T1 mutant without enzyme activity |
489189 |
| 2.4.1.41 | D209E |
ppGaNTase-T1 mutant with very low enzyme activity |
489189 |
| 2.4.1.41 | D209N |
ppGaNTase-T1 mutant without enzyme activity |
489189 |
| 2.4.1.41 | D261N |
naturally occuring mutation, the mutant activity is slightly reduced compared to the wild-type enzyme |
706506 |
| 2.4.1.41 | D303N |
naturally occuring mutation, the mutant activity is reduced by 60% compared to the wild-type enzyme |
706506 |
