EC Number |
Protein Variants |
Reference |
---|
1.3.3.4 | A172V |
site-directed mutagenesis, 99.8% reduced activity compared to the wild-type enzyme, 99% complementation of enzyme-deficient Escherichia coli strain SAS38X |
655194 |
1.3.3.4 | A433P |
reduced activity |
391007 |
1.3.3.4 | D143V |
site-directed mutagenesis, 99.6% reduced activity compared to the wild-type enzyme, 89% complementation of enzyme-deficient Escherichia coli strain SAS38X |
655194 |
1.3.3.4 | D349A |
the mutant enzyme maintains 8.05% of wild type activity |
764083 |
1.3.3.4 | D349E |
the mutant enzyme maintains 84.78% of wild type activity |
764083 |
1.3.3.4 | D349R |
the mutant enzyme maintains 2.48% of wild type activity |
764083 |
1.3.3.4 | del281H |
site-directed mutagenesis, inactive mutant, no complementation of enzyme-deficient Escherichia coli strain SAS38X |
655194 |
1.3.3.4 | E39A |
site-directed mutagenesis, inactive mutant |
744202 |
1.3.3.4 | E39D |
site-directed mutagenesis, the enzyme mutant shows 81% reduced activity compared to the wild-type enzyme |
744202 |
1.3.3.4 | E39K |
site-directed mutagenesis, inactive mutant |
744202 |