Information on EC 1.3.3.4 - protoporphyrinogen oxidase

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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria

EC NUMBER
COMMENTARY hide
1.3.3.4
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RECOMMENDED NAME
GeneOntology No.
protoporphyrinogen oxidase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
protoporphyrinogen IX + 3 O2 = protoporphyrin IX + 3 H2O2
show the reaction diagram
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
oxidation
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redox reaction
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reduction
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PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
3,8-divinyl-chlorophyllide a biosynthesis I (aerobic, light-dependent)
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3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)
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Biosynthesis of secondary metabolites
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heme biosynthesis I (aerobic)
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heme metabolism
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Metabolic pathways
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Porphyrin and chlorophyll metabolism
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superpathway of heme biosynthesis from uroporphyrinogen-III
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SYSTEMATIC NAME
IUBMB Comments
protoporphyrinogen-IX:oxygen oxidoreductase
This is the last common enzyme in the biosynthesis of chlorophylls and heme [8]. Two isoenzymes exist in plants: one in plastids and the other in mitochondria. This is the target enzyme of phthalimide-type and diphenylether-type herbicides [8]. The enzyme from oxygen-dependent species contains FAD [9]. Also slowly oxidizes mesoporphyrinogen IX.
CAS REGISTRY NUMBER
COMMENTARY hide
53986-32-6
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ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
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Manually annotated by BRENDA team
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Manually annotated by BRENDA team
propagated in HeLa cells, gene hemG
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Manually annotated by BRENDA team
Chlamydia trachomatis LGV-L2 434/Bu
propagated in HeLa cells, gene hemG
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Manually annotated by BRENDA team
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Manually annotated by BRENDA team
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UniProt
Manually annotated by BRENDA team
anaerobic, 2,6-dichlorophenolindophenol as electron acceptor
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Manually annotated by BRENDA team
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Manually annotated by BRENDA team
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Manually annotated by BRENDA team
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Manually annotated by BRENDA team
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Manually annotated by BRENDA team
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Manually annotated by BRENDA team
cv. LCP 85-384
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Manually annotated by BRENDA team
potato
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Manually annotated by BRENDA team
gene hemY or slr1790
UniProt
Manually annotated by BRENDA team
synthetic construct
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AY916795
GenBank
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
metabolism
physiological function
additional information
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
coproporphyrinogen-I + 3 O2
coproporphyrin-I + 3 H2O2
show the reaction diagram
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oxidized at less than 11% of the rate of protoporphyrinogen-IX
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?
coproporphyrinogen-III + 3 O2
coproporphyrin-III + 3 H2O2
show the reaction diagram
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?
hematoporphyrinogen-IX + 3 O2
hematoporphyrin-IX + 3 H2O2
show the reaction diagram
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?
mesoporphyrinogen-IX + 3 O2
mesoporphyrin-IX + 3 H2O2
show the reaction diagram
protoporphyrinogen IX + 3 O2
protoporphyrin + 3 H2O2
show the reaction diagram
protoporphyrinogen IX + 3 O2
protoporphyrin IX + 3 H2O2
show the reaction diagram
protoporphyrinogen-IX + 3 2,6-dichlorophenolindophenol
protoporphyrin-IX + 3 reduced 2,6-dichlorophenolindophenol
show the reaction diagram
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anaerobic bacterium, electron acceptor other than O2 required, does not utilize NAD(P)+, FAD or FMN
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?
protoporphyrinogen-IX + 3 O2
protoporphyrin-IX + 3 H2O2
show the reaction diagram
uroporphyrinogen-I + 3 O2
uroporphyrin-I + 3 H2O2
show the reaction diagram
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oxidized at less than 11% of the rate of protoporphyrinogen-IX
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?
additional information
?
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NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
protoporphyrinogen IX + 3 O2
protoporphyrin + 3 H2O2
show the reaction diagram
protoporphyrinogen IX + 3 O2
protoporphyrin IX + 3 H2O2
show the reaction diagram
protoporphyrinogen-IX + 3 O2
protoporphyrin-IX + 3 H2O2
show the reaction diagram
additional information
?
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COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
flavin
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Iron
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cofactor
additional information
INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(2,4-dichlorophenyl)hydrazine
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(2-bromo-4-fluorophenyl)hydrazine
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(4-chloro-2-fluorophenyl)hydrazine
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1-(2-chloro-5-(1,3-dioxo-4,5,6,7-tetrahydro-1H-isoindol-2(3H)-yl)-4-fluorophenyl)-3-(3-(trifluoromethyl)phenyl)urea
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1-(2-chloro-5-(1,3-dioxo-4,5,6,7-tetrahydro-1H-isoindol-2(3H)-yl)-4-fluorophenyl)-3-(4-chlorophenyl)urea
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1-(2-chloro-5-(1,3-dioxo-4,5,6,7-tetrahydro-1H-isoindol-2(3H)-yl)-4-fluorophenyl)-3-methylurea
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1-(4-chlorophenyl)-3-[2,4-dichloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]phenyl]urea
1-[2,4-dichloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]phenyl]-3-phenylurea
1-[2-(allylthio)-6-bromobenzothiazol-5-yl]-3-methyl-4-difluoromethyl-1H-1,2,4-triazol-5(4H)-one
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1-[2-(allylthio)-6-chlorobenzothiazol-5-yl]-3-methyl-4-difluoromethyl-1H-1,2,4-triazol-5(4H)-one
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1-[2-(allylthio)-6-fluorobenzothiazol-5-yl]-3-methyl-4-difluoromethyl-1H-1,2,4-triazol-5(4H)-one
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1-[2-(butylthio)-6-chlorobenzothiazol-5-yl]-3-methyl-4-difluoromethyl-1H-1,2,4-triazol-5(4H)-one
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1-[2-(butylthio)-6-fluorobenzothiazol-5-yl]-3-methyl-4-difluoromethyl-1H-1,2,4-triazol-5(4H)-one
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1-[2-bromo-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl]-3-(4-chlorophenyl)urea
1-[2-bromo-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl]-3-phenylurea
1-[4-bromo-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-2-fluorophenyl]-3-(4-chlorophenyl)urea
1-[4-bromo-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-2-fluorophenyl]-3-phenylurea
1-[4-chloro-3-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]phenyl]-3-(4-chlorophenyl)urea
1-[4-chloro-3-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]phenyl]-3-phenylurea
1-[6-chloro-2-(methylthio)benzothiazol-5-yl]-3-methyl-4-difluoromethyl-1H-1,2,4-triazol-5(4H)-one
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1-[6-chloro-2-(propylthio)benzothiazol-5-yl]-3-methyl-4-difluoromethyl-1H-1,2,4-triazol-5(4H)-one
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1-[6-fluoro-2-(methylthio)benzothiazol-5-yl]-3-methyl-4-difluoromethyl-1H-1,2,4-triazol-5(4H)-one
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1-[6-fluoro-2-(propylthio)benzothiazol-5-yl]-3-methyl-4-difluoromethyl-1H-1,2,4-triazol-5(4H)-one
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2,2'-[[4-(5,7-dimethyl-4-oxo-4,7-dihydro-3H-pyrazolo[3,4-d][1,2,3]triazin-3-yl)-5-fluorobenzene-1,2-diyl]bis(oxy)]bis(N-prop-2-en-1-ylacetamide)
2,2'-[[4-(5,7-dimethyl-4-oxo-4,7-dihydro-3H-pyrazolo[3,4-d][1,2,3]triazin-3-yl)-5-fluorobenzene-1,2-diyl]bis(oxy)]bis(N-prop-2-yn-1-ylacetamide)
2,2'-[[4-fluoro-5-(4-oxo-6-prop-2-en-1-yl-4,6-dihydro-3H-pyrazolo[3,4-d][1,2,3]triazin-3-yl)benzene-1,2-diyl]bis(oxy)]bis(N-prop-2-en-1-ylacetamide)
2,2'-[[4-fluoro-5-(4-oxo-6-prop-2-en-1-yl-4,6-dihydro-3H-pyrazolo[3,4-d][1,2,3]triazin-3-yl)benzene-1,2-diyl]bis(oxy)]bis(N-prop-2-yn-1-ylacetamide)
2,2'-[[4-fluoro-5-(4-oxo-6-propyl-4,6-dihydro-3H-pyrazolo[3,4-d][1,2,3]triazin-3-yl)benzene-1,2-diyl]bis(oxy)]bis(N-prop-2-en-1-ylacetamide)
2,2'-[[4-fluoro-5-(4-oxo-6-propyl-4,6-dihydro-3H-pyrazolo[3,4-d][1,2,3]triazin-3-yl)benzene-1,2-diyl]bis(oxy)]bis(N-prop-2-yn-1-ylacetamide)
2,2'-[[4-fluoro-5-(4-oxo-7-prop-2-en-1-yl-4,7-dihydro-3H-pyrazolo[3,4-d][1,2,3]triazin-3-yl)benzene-1,2-diyl]bis(oxy)]bis(N-prop-2-en-1-ylacetamide)
2,2'-[[4-fluoro-5-(4-oxo-7-prop-2-en-1-yl-4,7-dihydro-3H-pyrazolo[3,4-d][1,2,3]triazin-3-yl)benzene-1,2-diyl]bis(oxy)]bis(N-prop-2-yn-1-ylacetamide)
2,2'-[[4-fluoro-5-(4-oxo-7-propyl-4,7-dihydro-3H-pyrazolo[3,4-d][1,2,3]triazin-3-yl)benzene-1,2-diyl]bis(oxy)]bis(N-prop-2-en-1-ylacetamide)
2,2'-[[4-fluoro-5-(4-oxo-7-propyl-4,7-dihydro-3H-pyrazolo[3,4-d][1,2,3]triazin-3-yl)benzene-1,2-diyl]bis(oxy)]bis(N-prop-2-yn-1-ylacetamide)
2,2'-[[4-fluoro-5-(7-methyl-4-oxo-4,7-dihydro-3H-pyrazolo[3,4-d][1,2,3]triazin-3-yl)benzene-1,2-diyl]bis(oxy)]bis(N-prop-2-en-1-ylacetamide)
2,2'-[[4-fluoro-5-(7-methyl-4-oxo-4,7-dihydro-3H-pyrazolo[3,4-d][1,2,3]triazin-3-yl)benzene-1,2-diyl]bis(oxy)]bis(N-prop-2-yn-1-ylacetamide)
2,2'-[[4-fluoro-5-(7-methyl-4-oxo-4,7-dihydro-3H-pyrazolo[3,4-d][1,2,3]triazin-3-yl)benzene-1,2-diyl]bis(oxy)]bis(N-propylacetamide)
2,2'-[[4-fluoro-5-[7-methyl-4-oxo-5-(trifluoromethyl)-4,7-dihydro-3H-pyrazolo[3,4-d][1,2,3]triazin-3-yl]benzene-1,2-diyl]bis(oxy)]bis(N-prop-2-en-1-ylacetamide)
2,2'-[[4-fluoro-5-[7-methyl-4-oxo-5-(trifluoromethyl)-4,7-dihydro-3H-pyrazolo[3,4-d][1,2,3]triazin-3-yl]benzene-1,2-diyl]bis(oxy)]bis(N-prop-2-yn-1-ylacetamide)
2,4-dichloro-N-(2-chloro-5-(1,3-dioxo-4,5,6,7-tetrahydro-1H-isoindol-2(3H)-yl)-4-fluorophenylcarbamoyl)benzamide
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2,6-dichloro-N-(2-chloro-5-(1,3-dioxo-4,5,6,7-tetrahydro-1H-isoindol-2(3H)-yl)-4-fluorophenylcarbamoyl)benzamide
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2-(2,4-dichloro-5-propoxyphenyl)-2,3,4,5,6,7-hexahydro-1H-isoindol-1-one
2-(3-amino-4-chlorophenyl)-2,3,4,5,6,7-hexahydro-1H-isoindol-1-one
2-(3-oxo-4-prop-2-yn-1-yl-3,4-dihydro-2H-1,4-benzoxazin-6-yl)-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione
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2-(4-bromo-2-fluoro-5-hydroxyphenyl)-3-(prop-2-en-1-yloxy)-2,3,4,5,6,7-hexahydro-1H-isoindol-1-one
2-(4-bromo-2-fluoro-5-hydroxyphenyl)-3-hydroxy-2,3,4,5,6,7-hexahydro-1H-isoindol-1-one
2-(4-chloro-2-ethoxy-5-nitrophenyl)-3-hydroxy-2,3,4,5,6,7-hexahydro-1H-isoindol-1-one
2-(4-chloro-2-fluoro-5-methoxyphenyl)-3-hydroxyoctahydro-1H-isoindol-1-one
2-(4-chloro-2-fluoro-5-methoxyphenyl)-3-methoxy-2,3,4,5,6,7-hexahydro-1H-isoindol-1-one
2-(4-chloro-2-fluoro-5-methoxyphenyl)hexahydro-1H-isoindole-1,3(2H)-dione
2-(4-chloro-2-fluoro-5-propoxy-phenyl)-2,3,4,5,6,7-hexahydro-isoindol-1-one
2-(4-chloro-2-fluoro-5-[(3-fluorobenzyl)oxy]phenyl)-3-hydroxy-2,3,4,5,6,7-hexahydro-1H-isoindol-1-one
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2-(4-chloro-5-ethoxy-2-fluorophenyl)-2,3,4,5,6,7-hexahydro-1H-isoindol-1-one
2-(4-chloro-5-[(3-chlorobenzyl)oxy]-2-fluorophenyl)-3-(prop-2-en-1-yloxy)-2,3,4,5,6,7-hexahydro-1H-isoindol-1-one
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2-(4-chloro-5-[(3-chlorobenzyl)oxy]-2-fluorophenyl)-3-ethoxy-2,3,4,5,6,7-hexahydro-1H-isoindol-1-one
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2-(4-chloro-5-[(3-chlorobenzyl)oxy]-2-fluorophenyl)-3-methoxy-2,3,4,5,6,7-hexahydro-1H-isoindol-1-one
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2-(5-allyloxy-4-chloro-2-fluorophenyl)-2,3,4,5,6,7-hexahydro-isoindol-1-one
2-(6-(1,3-dioxoisoindolin-2-yl)-7-fluoro-3-oxo-2H-benzo[b][1,4]oxazin-4(3H)-yl)acetonitrile
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2-(7-fluoro-2-methyl-3-oxo-4-(prop-2-ynyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-5-methylisoindoline-1,3-dione
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2-(7-fluoro-3-oxo-4-(prop-2-ynyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-5-methylisoindoline-1,3-dione
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2-(7-fluoro-3-oxo-4-(prop-2-ynyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)isoindoline-1,3-dione
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2-chloro-4-fluoro-5-(7-methyl-4-oxo-4,7-dihydro-3H-pyrazolo[3,4-d][1,2,3]triazin-3-yl)phenyl ethyl carbonate
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2-chloro-N-(2-chloro-5-(1,3-dioxo-4,5,6,7-tetrahydro-1H-isoindol-2(3H)-yl)-4-fluorophenylcarbamoyl)-6-fluorobenzamide
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2-[2,4-dichloro-5-(prop-2-en-1-yloxy)phenyl]-3-hydroxy-2,3,4,5,6,7-hexahydro-1H-isoindol-1-one
2-[2,4-dichloro-5-(prop-2-yn-1-yloxy)phenyl]-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one
2-[2,4-dichloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]phenyl]-1H-isoindole-1,3(2H)-dione
2-[2,4-dichloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]phenyl]-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione
2-[2,4-dichloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]phenyl]hexahydro-1H-isoindole-1,3(2H)-dione
2-[2-bromo-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl]-1H-isoindole-1,3(2H)-dione
2-[2-bromo-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl]-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione
2-[2-bromo-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl]hexahydro-1H-isoindole-1,3(2H)-dione
2-[4-bromo-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-2-fluorophenyl]-1H-isoindole-1,3(2H)-dione
2-[4-bromo-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-2-fluorophenyl]-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione
2-[4-bromo-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-2-fluorophenyl]hexahydro-1H-isoindole-1,3(2H)-dione
2-[4-chloro-2-fluoro-5-(prop-2-en-1-yloxy)phenyl]-3-(prop-2-en-1-yloxy)-2,3,4,5,6,7-hexahydro-1H-isoindol-1-one
2-[4-chloro-2-fluoro-5-(prop-2-en-1-yloxy)phenyl]-3-hydroxy-2,3,4,5,6,7-hexahydro-1H-isoindol-1-one
2-[4-chloro-2-fluoro-5-(prop-2-en-1-yloxy)phenyl]-3-hydroxyoctahydro-1H-isoindol-1-one
2-[4-chloro-2-fluoro-5-(prop-2-yn-1-yloxy)phenyl]-3-hydroxyoctahydro-1H-isoindol-1-one
2-[4-chloro-2-fluoro-5-(propan-2-yloxy)phenyl]-2,3,4,5,6,7-hexahydro-1H-isoindol-1-one
2-[4-chloro-3-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]phenyl]-1H-isoindole-1,3(2H)-dione
2-[4-chloro-3-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]phenyl]-4,5,6,7-tetrahydro-1H-isoindole-1,3(2H)-dione
2-[4-chloro-3-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]phenyl]hexahydro-1H-isoindole-1,3(2H)-dione
2-[4-chloro-5-(cyclopentyloxy)-2-fluorophenyl]-3-hydroxyoctahydro-1H-isoindol-1-one
2-[4-fluoro-3-(7-methyl-4-oxo-4,7-dihydro-3H-pyrazolo[3,4-d][1,2,3]triazin-3-yl)phenoxy]-N-prop-2-en-1-ylacetamide
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2-[4-fluoro-5-(7-methyl-4-oxo-4,7-dihydro-3H-pyrazolo[3,4-d][1,2,3]triazin-3-yl)-2-[2-oxo-2-(prop-2-en-1-ylamino)ethoxy]phenoxy]-N-propylacetamide
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2-[5-(4-difluoromethyl-3-methyl-5-oxo-4,5-dihydro-1,2,4-triazol-1-yl)-6-fluorobenzothiazol-2-ylthio]acetic acid
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2-[5-(4-difluoromethyl-3-methyl-5-oxo-4,5-dihydro-1,2,4-triazol-1-yl)-6-fluorobenzothiazol-2-ylthio]propanoic acid
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2-[6-bromo-2-(prop-2-en-1-ylsulfanyl)-1,3-benzothiazol-5-yl]-4-(difluoromethyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one
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2-[6-chloro-5-(4-difluoromethyl-3-methyl-5-oxo-4,5-dihydro-1,2,4-triazol-1-yl)benzothiazol-2-ylthio]acetic acid
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2-[6-chloro-5-(4-difluoromethyl-3-methyl-5-oxo-4,5-dihydro-1,2,4-triazol-1-yl)benzothiazol-2-ylthio]propanoic acid
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2-{4-chloro-2-fluoro-5-[(3-fluorobenzyl)oxy]phenyl}-3-hydroxy-2,3,4,5,6,7-hexahydro-1H-isoindol-1-one
2-{4-chloro-5-[(3-chlorobenzyl)oxy]-2-fluorophenyl}-3-(prop-2-en-1-yloxy)-2,3,4,5,6,7-hexahydro-1H-isoindol-1-one
2-{4-chloro-5-[(3-chlorobenzyl)oxy]-2-fluorophenyl}-3-ethoxy-2,3,4,5,6,7-hexahydro-1H-isoindol-1-one
2-{4-chloro-5-[(3-chlorobenzyl)oxy]-2-fluorophenyl}-3-methoxy-2,3,4,5,6,7-hexahydro-1H-isoindol-1-one
3-(2-bromo-4-fluoro-5-nitrophenyl)-5-tert-butyl-1,3,4-oxadiazol-2(3H)-one
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3-(2-bromo-4-fluorophenyl)-5-tert-butyl-1,3,4-oxadiazol-2(3H)-one
-
-
3-(2-chloro-5-(1,3-dioxo-4,5,6,7-tetrahydro-1H-isoindol-2(3H)-yl)-4-fluorophenyl)-1,1-diisopropylurea
-
-
3-(2-chloro-5-(1,3-dioxo-4,5,6,7-tetrahydro-1H-isoindol-2(3H)-yl)phenyl)-1,1-diisopropylurea
-
-
3-(4-chloro-2-fluoro-5-hydroxyphenyl)-7-methyl-3,7-dihydro-4H-pyrazolo[3,4-d][1,2,3]triazin-4-one
3-(4-chloro-2-fluoro-5-methoxyphenyl)-7-methyl-3,7-dihydro-4H-pyrazolo[3,4-d][1,2,3]triazin-4-one
3-(4-chloro-2-fluoro-5-propoxyphenyl)-7-methyl-3,7-dihydro-4H-pyrazolo[3,4-d][1,2,3]triazin-4-one
3-(4-chloro-5-ethoxy-2-fluorophenyl)-7-methyl-3,7-dihydro-4H-pyrazolo[3,4-d][1,2,3]triazin-4-one
3-(5-amino-2,4-dichlorophenyl)-5-tert-butyl-1,3,4-oxadiazol-2(3H)-one
-
-
3-(5-amino-2-bromo-4-fluorophenyl)-5-tert-butyl-1,3,4-oxadiazol-2(3H)-one
-
-
3-(5-amino-4-chloro-2-fluorophenyl)-5-tert-butyl-1,3,4-oxadiazol-2(3H)-one
-
-
3-(5-butoxy-4-chloro-2-fluorophenyl)-7-methyl-3,7-dihydro-4H-pyrazolo[3,4-d][1,2,3]triazin-4-one
3-(6-bromo-2-[(3-methylbut-2-en-1-yl)sulfanyl]-1,3-benzothiazol-5-yl)-5-tert-butyl-1,3,4-oxadiazol-2(3H)-one
-
-
-
3-chloro-N-(2-chloro-5-(1,3-dioxo-4,5,6,7-tetrahydro-1H-isoindol-2(3H)-yl)-4-fluorophenyl)-2,2-dimethylpropanamide
-
-
3-[4-chloro-2-fluoro-5-(pentyloxy)phenyl]-7-methyl-3,7-dihydro-4H-pyrazolo[3,4-d][1,2,3]triazin-4-one
3-[4-chloro-2-fluoro-5-(prop-2-en-1-yloxy)phenyl]-5,7-dimethyl-3,7-dihydro-4H-pyrazolo[3,4-d][1,2,3]triazin-4-one
3-[4-chloro-2-fluoro-5-(prop-2-en-1-yloxy)phenyl]-6-prop-2-en-1-yl-3,6-dihydro-4H-pyrazolo[3,4-d][1,2,3]triazin-4-one
3-[4-chloro-2-fluoro-5-(prop-2-en-1-yloxy)phenyl]-7-methyl-3,7-dihydro-4H-pyrazolo[3,4-d][1,2,3]triazin-4-one
3-[4-chloro-2-fluoro-5-(prop-2-en-1-yloxy)phenyl]-7-prop-2-en-1-yl-3,7-dihydro-4H-pyrazolo[3,4-d][1,2,3]triazin-4-one
3-[4-chloro-2-fluoro-5-(prop-2-yn-1-yloxy)phenyl]-5,7-dimethyl-3,7-dihydro-4H-pyrazolo[3,4-d][1,2,3]triazin-4-one
3-[4-chloro-2-fluoro-5-(prop-2-yn-1-yloxy)phenyl]-6-prop-2-en-1-yl-3,6-dihydro-4H-pyrazolo[3,4-d][1,2,3]triazin-4-one
3-[4-chloro-2-fluoro-5-(prop-2-yn-1-yloxy)phenyl]-7-methyl-3,7-dihydro-4H-pyrazolo[3,4-d][1,2,3]triazin-4-one
3-[4-chloro-2-fluoro-5-(prop-2-yn-1-yloxy)phenyl]-7-methyl-5-(trifluoromethyl)-3,7-dihydro-4H-pyrazolo[3,4-d][1,2,3]triazin-4-one
3-[4-chloro-2-fluoro-5-(prop-2-yn-1-yloxy)phenyl]-7-prop-2-en-1-yl-3,7-dihydro-4H-pyrazolo[3,4-d][1,2,3]triazin-4-one
3-[4-chloro-2-fluoro-5-[(2-methoxyethoxy)methoxy]phenyl]-7-methyl-3,7-dihydro-4H-pyrazolo[3,4-d][1,2,3]triazin-4-one
3-[4-chloro-5-(cyclohexyloxy)-2-fluorophenyl]-7-methyl-3,7-dihydro-4H-pyrazolo[3,4-d][1,2,3]triazin-4-one
-
-
3-[4-chloro-5-[(2-chloroprop-2-en-1-yl)oxy]-2-fluorophenyl]-7-methyl-3,7-dihydro-4H-pyrazolo[3,4-d][1,2,3]triazin-4-one
3-[4-chloro-5-[(3-chloroprop-2-en-1-yl)oxy]-2-fluorophenyl]-7-methyl-3,7-dihydro-4H-pyrazolo[3,4-d][1,2,3]triazin-4-one
3-[5-[4-difluoromethyl-3-methyl-5-oxo-4,5-dihydro-1,2,4-triazol-1-yl]-6-fluorobenzothiazol-2-ylthio]propanoic acid
-
-
3-[6-bromo-2-(prop-2-yn-1-ylsulfanyl)-1,3-benzothiazol-5-yl]-5-tert-butyl-1,3,4-oxadiazol-2(3H)-one
-
-
3-[6-bromo-2-(prop-2-yn-1-ylsulfanyl)-1,3-benzothiazol-5-yl]-5-tert-butyl-1,3,4-thiadiazol-2(3H)-one
-
-
3-[6-chloro-5-[4-difluoromethyl-3-methyl-5-oxo-4,5-dihydro-1,2,4-triazol-1-yl]benzothiazol-2-ylthio]propanoic acid
-
-
4-bromo-3-(5'-carboxy-4'-chloro-2'-fluoro-phenyl)-1-methyl-5-trifluoromethyl-pyrazol
-
4-chloro-phthalimide
4-fluoro-2-(7-fluoro-2-methyl-3-oxo-4-(prop-2-ynyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)isoindoline-1,3-dione
-
-
5-tert-butyl-3-(2,4-dichloro-5-nitrophenyl)-1,3,4-oxadiazol-2(3H)-one
-
-
5-tert-butyl-3-(2,4-dichlorophenyl)-1,3,4-oxadiazol-2(3H)-one
-
-
5-tert-butyl-3-(2-[(3,3-dichloroprop-2-en-1-yl)sulfanyl]-6-fluoro-1,3-benzothiazol-5-yl)-1,3,4-oxadiazol-2(3H)-one
-
-
-
5-tert-butyl-3-(4-chloro-2-fluoro-5-nitrophenyl)-1,3,4-oxadiazol-2(3H)-one
-
-
5-tert-butyl-3-(4-chloro-2-fluorophenyl)-1,3,4-oxadiazol-2(3H)-one
-
-
5-tert-butyl-3-(6-chloro-2-[(3,3-dichloroprop-2-en-1-yl)sulfanyl]-1,3-benzothiazol-5-yl)-1,3,4-oxadiazol-2(3H)-one
-
-
-
5-tert-butyl-3-[6-chloro-2-(prop-2-en-1-ylsulfanyl)-1,3-benzothiazol-5-yl]-1,3,4-oxadiazol-2(3H)-one
-
-
5-tert-butyl-3-[6-chloro-2-(prop-2-yn-1-ylsulfanyl)-1,3-benzothiazol-5-yl]-1,3,4-oxadiazol-2(3H)-one
-
-
5-tert-butyl-3-[6-chloro-2-(prop-2-yn-1-ylsulfanyl)-1,3-benzothiazol-5-yl]-1,3,4-thiadiazol-2(3H)-one
-
-
5-tert-butyl-3-[6-fluoro-2-(prop-2-en-1-ylsulfanyl)-1,3-benzothiazol-5-yl]-1,3,4-oxadiazol-2(3H)-one
-
-
5-tert-butyl-3-[6-fluoro-2-(prop-2-yn-1-ylsulfanyl)-1,3-benzothiazol-5-yl]-1,3,4-oxadiazol-2(3H)-one
-
-
5-tert-butyl-3-[6-fluoro-2-(prop-2-yn-1-ylsulfanyl)-1,3-benzothiazol-5-yl]-1,3,4-thiadiazol-2(3H)-one
-
-
5-[2-chloro-4-(trifluoromethyl)phenoxyl]-2-nitrobenzoic acid
-
transgenic YZI-1S cells show a 150fold greater resistance to the inhibitor compared to wild-type cells, inhibition of mitochondrial and chloroplastic isozymes
acifluoren
light-dependent peroxidizing diphenyl ether herbicide
acifluorfen
Acifluorfen-methyl
arsenite
-
slight inhibition
ascorbate
-
-
azafenidin
bilirubin
Biliverdin
-
competitive
biliverdin IX hydrochloride
-
inhibition potency with recombinant wild-type and mutant enzymes, overview
butafenacil
-
0.0001 mM
carfentrazone
-
-
carfentrazone-ethyl
chlorphthalim
Co2+
-
inhibitory
cobalt-protoporphyrin
-
-
coenzyme Q0
-
above 0.03 mM
Cu2+
-
inhibitory
dicoumarol
-
above 0.03 mM
diphenylene iodonium
DTT
-
inhibits activity of N-terminally processed-like enzyme form
ethyl ([5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl)acetate
-
-
-
ethyl ([5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl)acetate
-
-
-
ethyl ([6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-1,3-benzothiazol-2-yl]sulfanyl)acetate
-
-
-
ethyl 1-[5-[4-difluoromethyl-3-methyl-5-oxo-4,5-dihydro-1,2,4-triazol-1-yl]-6-fluoro benzothiazol-2-ylthio]acetate
-
-
ethyl 1-[5-[4-difluoromethyl-3-methyl-5-oxo-4,5-dihydro-1,2,4-triazol-1-yl]-6-fluoro benzothiazol-2-ylthio]propanoate
-
-
ethyl 1-[6-bromo-5-[4-difluoromethyl-3-methyl-5-oxo-4,5-dihydro-1,2,4-triazol-1-yl] benzothiazol-2-ylthio]acetate
-
-
ethyl 1-[6-chloro-5-[4-difluoromethyl-3-methyl-5-oxo-4,5-dihydro-1,2,4-triazol-1-yl] benzothiazol-2-ylthio]acetate
-
-
ethyl 1-[6-chloro-5-[4-difluoromethyl-3-methyl-5-oxo-4,5-dihydro-1,2,4-triazol-1-yl] benzothiazol-2-ylthio]propanoate
-
-
ethyl 2-((5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-2(3H)-yl)-6-fluorobenzothiazol-2-yl)sulfanyl)propanoate
-
with a broad spectrum of postemergence herbicidal activity
ethyl 2-(6-(1,3-dioxo-4,5,6,7-tetrahydro-1H-isoindol-2(3H)-yl)-7-fluoro-2-methyl-3-oxo-2H-benzo[b][1,4]oxazin-4(3H)-yl)-2-phenylacetate
-
-
ethyl 2-(6-(1,3-dioxo-4,5,6,7-tetrahydro-1H-isoindol-2(3H)-yl)-7-fluoro-2-methyl-3-oxo-2H-benzo[b][1,4]oxazin-4(3H)-yl)acetate
-
-
ethyl 2-(6-(1,3-dioxo-4,5,6,7-tetrahydro-1H-isoindol-2(3H)-yl)-7-fluoro-2-methyl-3-oxo-2H-benzo[b][1,4]oxazin-4(3H)-yl)propanoate
-
-
ethyl 2-(6-(1,3-dioxo-4,5,6,7-tetrahydro-1H-isoindol-2(3H)-yl)-7-fluoro-3-oxo-2H-benzo[b][1,4]oxazin-4(3H)-yl)butanoate
-
-
ethyl 2-(6-(1,3-dioxo-4,5,6,7-tetrahydro-1H-isoindol-2(3H)-yl)-7-fluoro-3-oxo-2H-benzo[b][1,4]oxazin-4(3H)-yl)propanoate
-
-
ethyl 2-([5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl)-2-methylpropanoate
-
-
-
ethyl 2-([5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl)-2-methylpropanoate
-
-
-
ethyl 2-([6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-1,3-benzothiazol-2-yl]sulfanyl)propanoate
-
-
-
ethyl 2-chloro-3-[2-chloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]-4-fluorophenyl]propanoate
ethyl 2-[2-chloro-4-fluoro-5-(1-hydroxy-3-oxooctahydro-2H-isoindol-2-yl)phenoxy]propanoate
ethyl 2-[2-chloro-5-(1,3-dioxooctahydro-2H-isoindol-2-yl)-4-fluorophenoxy]propanoate
ethyl 3 ([5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl)propanoate
-
-
-
ethyl 3-([5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl)butanoate
-
-
-
ethyl 3-([5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl)propanoate
-
-
-
ethyl 3-([5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl)propanoate
-
-
-
ethyl 3-([6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-1,3-benzothiazol-2-yl]sulfanyl)propanoate
-
-
-
ethyl 4-([5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl)butanoate
-
-
-
ethyl 4-([5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl)butanoate
-
-
-
ethyl 4-([6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-1,3-benzothiazol-2-yl]sulfanyl)butanoate
-
-
-
ethyl [2-chloro-4-fluoro-5-(1-hydroxy-3-oxooctahydro-2H-isoindol-2-yl)phenoxy]acetate
ethyl [2-chloro-5-(1,3-dioxooctahydro-2H-isoindol-2-yl)-4-fluorophenoxy]acetate
ethyl [[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]acetate
-
-
ethyl [[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]acetate
-
-
flumioxazin
glutathione
imazapyr
-
-
iodoacetamide
iodoacetate
-
slight inhibition
menadione
-
above 0.03 mM
metalloporphyrin
-
Mn- and Co-protoporphyrin, weak inhibition by Cd-, Ni- and Fe-protoporphyrin, 5 min preincubation
-
methyl (2E)-4-([5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl)but-2-enoate
-
-
-
methyl ([5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl)acetate
-
-
-
methyl ([5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl)acetate
-
-
-
methyl ([6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-1,3-benzothiazol-2-yl]sulfanyl)acetate
-
-
-
methyl 1-[6-chloro-5-[4-difluoromethyl-3-methyl-5-oxo-4,5-dihydro-1,2,4-triazol-1-yl] benzothiazol-2-ylthio]acetate
-
-
methyl 2-((5-(1,3-dioxo-4,5,6,7-tetrahydro-1H-isoindol-2(3H)-yl)-6-fluorobenzothiazol-2-yl)thio)acetate
-
-
methyl 2-(6-(1,3-dioxo-4,5,6,7-tetrahydro-1H-isoindol-2(3H)-yl)-7-fluoro-2-methyl-3-oxo-2H-benzo[b][1,4]oxazin-4(3H)-yl)acetate
-
-
methyl 2-(6-(1,3-dioxo-4,5,6,7-tetrahydro-1H-isoindol-2(3H)-yl)-7-fluoro-2-methyl-3-oxo-2H-benzo[b][1,4]oxazin-4(3H)-yl)propanoate
-
-
methyl 2-(6-(1,3-dioxo-4,5,6,7-tetrahydro-1H-isoindol-2(3H)-yl)-7-fluoro-3-oxo-2H-benzo[b][1,4]oxazin-4(3H)-yl)butanoate
-
-
methyl 2-[3-methyl-(2-fluoro-4-chloro-5-ethyl-sulfonamidephenyl)-4,5-dihydro-5-oxo-1H-1,2,4-triazol-4-yl]methylenephenyl-2-(E)-methoxyiminoacetate
methyl 2-[5-(4-difluoromethyl-3-methyl-5-oxo-4,5-dihydro-1,2,4-triazol-1-yl)-6-fluoro benzothiazol-2-ylthio]acetate
-
-
methyl acifluorfen
-
inhibition potency with recombinant wild-type and mutant enzymes, overview
methyl [2,4-dichloro-5-[4-(difluoromethyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]phenyl]amidosulfite
methyl [[5-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]acetate
-
-
methyl [[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]acetate
-
-
methyl [[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]acetate
-
-
methyl [[6-chloro-5-(1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl)-1,3-benzothiazol-2-yl]sulfanyl]acetate
-
-
N'-(2,4-dichlorophenyl)-2,2-dimethylpropanehydrazide
-
-
N'-(2-bromo-4-fluorophenyl)-2,2-dimethylpropanehydrazide
-
-
N'-(4-chloro-2-fluorophenyl)-2,2-dimethylpropanehydrazide
-
-
N-(2-chloro-5-(1,3-dioxo-4,5,6,7-tetrahydro-1H-isoindol-2(3H)-yl)-4-fluorophenylcarbamoyl)-3-(trifluoromethoxy)benzamide
-
-
N-(2-chloro-5-(1,3-dioxo-4,5,6,7-tetrahydro-1H-isoindol-2(3H)-yl)-4-fluorophenylcarbamoyl)benzamide
-
-
N-(2-chloro-5-(1,3-dioxo-4,5,6,7-tetrahydro-1H-isoindol-2(3H)-yl)phenylcarbamoyl)benzamide
-
-
N-(4-chloro-2-fuoro-5-(propargyloxy)phenyl)-3,4,5,6-tetrahydrophthalimide
N-ethylmaleimide
N-Methylprotoporphyrin
-
slight, 11% inhibition at 0.0001 mM
NaCl
-
inhibits recombinant wild-type enzyme and mutant V311M
NAD(P)H
-
-
NADH
-
inhibits activity of N-terminally processed-like enzyme form
NADPH
-
inhibits activity of N-terminally processed-like enzyme form
o-phenanthroline
-
in presence of glutathione
oxadiargyl
oxadiazon
oxyfluorfen
oxyfuorfen
oxyXuorfen
-
transgenic rice lines TTS3 and TTS4 exhibit a reduced Protox activity, however, it is much greater than that of uninhibited Protox activity of wild type, seeds from all transgenic lines are able to germinate when treated with up to 0.5 mM, whereas seeds from the wild-type fail to germinate even when treated at levels as low as 0.001 mM, great accumulation of photodynamic protoporphyrin IX only in oxyfuorfen-treated wild-type plants, not in oxyfuorfen-treated TTS lines
p-hydroxymercuribenzoate
paraquat
-
-
pentoxazone
phenyl 2-[[5-(1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]propanoate
-
-
phenyl 2-[[5-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]propanoate
-
-
phenyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl]-2-methylpropanoate
-
-
phenyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl]propanoate
-
-
phenyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]-2-methylpropanoate
-
-
phenyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]propanoate
-
-
phenyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3(2H)-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl]-2-methylpropanoate
-
-
phenyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3(2H)-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl]propanoate
-
-
phenyl 2-[[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]-2-methylpropanoate
-
-
phenyl 2-[[6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-1,3-benzothiazol-2-yl]sulfanyl]-2-methylpropanoate
-
-
phenyl 2-[[6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-1,3-benzothiazol-2-yl]sulfanyl]propanoate
-
-
phenyl 2-[[6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3(2H)-yl)-1,3-benzothiazol-2-yl]sulfanyl]-2-methylpropanoate
-
-
phenyl 2-[[6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3(2H)-yl)-1,3-benzothiazol-2-yl]sulfanyl]propanoate
-
-
phenyl 2-[[6-chloro-5-(1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl)-1,3-benzothiazol-2-yl]sulfanyl]-2-methylpropanoate
-
-
phenyl 2-[[6-chloro-5-(1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl)-1,3-benzothiazol-2-yl]sulfanyl]propanoate
-
-
phenyl 2-[[6-chloro-5-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-1,3-benzothiazol-2-yl]sulfanyl]propanoate
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-
phenyl 3-[[5-(1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]propanoate
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-
phenyl 3-[[5-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]propanoate
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-
phenyl 3-[[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl]propanoate
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-
phenyl 3-[[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3(2H)-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl]propanoate
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-
phenyl 3-[[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]propanoate
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-
phenyl 3-[[6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-1,3-benzothiazol-2-yl]sulfanyl]propanoate
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-
phenyl 3-[[6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3(2H)-yl)-1,3-benzothiazol-2-yl]sulfanyl]propanoate
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-
phenyl 3-[[6-chloro-5-(1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl)-1,3-benzothiazol-2-yl]sulfanyl]propanoate
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-
phenyl 3-[[6-chloro-5-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-1,3-benzothiazol-2-yl]sulfanyl]propanoate
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-
phenyl 4-[[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl]butanoate
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-
phenyl 4-[[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]butanoate
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phenyl 4-[[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3(2H)-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl]butanoate
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phenyl 4-[[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]butanoate
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-
phenyl 4-[[6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-1,3-benzothiazol-2-yl]sulfanyl]butanoate
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phenyl 4-[[6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3(2H)-yl)-1,3-benzothiazol-2-yl]sulfanyl]butanoate
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-
phenyl 4-[[6-chloro-5-(1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl)-1,3-benzothiazol-2-yl]sulfanyl]butanoate
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-
phenyl [[5-(1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]acetate
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-
phenyl [[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl]acetate
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-
phenyl [[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]acetate
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-
phenyl [[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3(2H)-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl]acetate
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-
phenyl [[6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-1,3-benzothiazol-2-yl]sulfanyl]acetate
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-
phenyl [[6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3(2H)-yl)-1,3-benzothiazol-2-yl]sulfanyl]acetate
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-
phenyl [[6-chloro-5-(1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl)-1,3-benzothiazol-2-yl]sulfanyl]acetate
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-
phosphatidylcholine
-
from egg and soybean
propan-2-yl ([5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl)acetate
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-
-
propan-2-yl ([5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl)acetate
-
-
-
propan-2-yl ([6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-1,3-benzothiazol-2-yl]sulfanyl)acetate
-
-
-
propan-2-yl [[5-(1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]acetate
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-
propan-2-yl [[5-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]acetate
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-
propan-2-yl [[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]acetate
-
-
propan-2-yl [[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]acetate
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-
propyl ([5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl)acetate
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-
-
propyl ([5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl)acetate
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-
-
propyl ([6-bromo-5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-1,3-benzothiazol-2-yl]sulfanyl)acetate
-
-
-
propyl [[5-(1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]acetate
-
-
propyl [[5-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]acetate
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-
propyl [[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]acetate
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-
propyl [[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]acetate
-
-
protoporphyrinogen-IX
-
substrate inhibition above 0.05 mM
S-(5-(1,3-dioxo-4,5,6,7-tetrahydro-1H-isoindol-2(3H)-yl)-6-fluorobenzothiazol-2-yl) O-methyl carbonothioate
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-
S-5-[4-difluoromethyl-3-methyl-5-oxo-4,5-dihydro-1,2,4-triazol-1-yl]-6-fluorobenzothiazol-2-yl O-ethyl carbonothioate
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-
S-5-[4-difluoromethyl-3-methyl-5-oxo-4,5-dihydro-1,2,4-triazol-1-yl]-6-fluorobenzothiazol-2-yl O-methyl carbonothioate
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-
S-6-chloro-5-[4-difluoromethyl-3-methyl-5-oxo-4,5-dihydro-1,2,4-triazol-1-yl]benzothiazol-2-yl O-ethyl carbonothioate
-
-
S-6-chloro-5-[4-difluoromethyl-3-methyl-5-oxo-4,5-dihydro-1,2,4-triazol-1-yl]benzothiazol-2-yl O-methyl carbonothioate
-
-
S-[5-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-6-fluoro-1,3-benzothiazol-2-yl] O-phenyl carbonothioate
-
-
S-[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-chloro-1,3-benzothiazol-2-yl] O-ethyl carbonothioate
-
-
S-[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-chloro-1,3-benzothiazol-2-yl] O-phenyl carbonothioate
-
-
S-[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl] O-ethyl carbonothioate
-
-
S-[5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl] O-methyl carbonothioate
-
-
S-[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3(2H)-yl)-6-chloro-1,3-benzothiazol-2-yl] O-phenyl carbonothioate
-
-
S-[5-(5-tert-butyl-2-oxo-1,3,4-thiadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl] O-ethyl carbonothioate
-
-
S-[6-chloro-5-(1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl)-1,3-benzothiazol-2-yl] O-methyl carbonothioate
-
-
S-[6-chloro-5-(1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl)-1,3-benzothiazol-2-yl] O-phenyl carbonothioate
-
-
sulfentrazone
tert-butyl ([5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-chloro-1,3-benzothiazol-2-yl]sulfanyl)acetate
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-
-
tert-butyl ([5-(5-tert-butyl-2-oxo-1,3,4-oxadiazol-3(2H)-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl)acetate
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-
-
tert-butyl [[5-(1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl)-6-fluoro-1,3-benzothiazol-2-yl]sulfanyl]acetate
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-
Ubiquinone-10
-
above 0.03 mM
ubiquinone-6
-
above 0.03 mM
[2-chloro-4-fluoro-5-(7-methyl-4-oxo-4,7-dihydro-3H-pyrazolo[3,4-d][1,2,3]triazin-3-yl)phenoxy]acetonitrile
[5-(t-butyl)-3-(2,4-dichloro-5-isopropoxyphenyl)-1,3,4-oxadiazol-2-one]
additional information