EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
   3.1.13.B1 | Amyotrophic Lateral Sclerosis |
32686621 |
SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation. |
causal interaction
therapeutic application
unassigned |
1
1
0 |
| 3.1.13.B1 | Apraxias |
32686621 |
SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation. |
causal interaction
therapeutic application
unassigned |
1
1
0 |
| 3.1.13.B1 | Ataxia |
32686621 |
SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation. |
causal interaction
therapeutic application
unassigned |
1
1
0 |
| 3.1.13.B1 | Choriocarcinoma |
31519749 |
Zika virus noncoding sfRNAs sequester multiple host-derived RNA-binding proteins and modulate mRNA decay and splicing during infection. |
causal interaction
unassigned |
1
0 |
| 3.1.13.B1 | Dengue |
31519749 |
Zika virus noncoding sfRNAs sequester multiple host-derived RNA-binding proteins and modulate mRNA decay and splicing during infection. |
causal interaction
unassigned |
1
0 |
| 3.1.13.B1 | Frontotemporal Dementia |
32686621 |
SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation. |
causal interaction
therapeutic application
unassigned |
1
1
0 |
| 3.1.13.B1 | Hepatitis C |
25747802 |
XRN1 Stalling in the 5' UTR of Hepatitis C Virus and Bovine Viral Diarrhea Virus Is Associated with Dysregulated Host mRNA Stability. |
therapeutic application
unassigned |
1
0 |
| 3.1.13.B1 | Infections |
17688902 |
Expression of the Arabidopsis Xrn4p 5'-3' exoribonuclease facilitates degradation of tombusvirus RNA and promotes rapid emergence of viral variants in plants. |
unassigned |
0 |
| 3.1.13.B1 | Muscular Atrophy, Spinal |
32686621 |
SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation. |
causal interaction
therapeutic application
unassigned |
1
1
0 |
| 3.1.13.B1 | Neoplasms |
33626405 |
Upregulation of XRN2 acts as an oncogene in oral squamous cell carcinoma and correlates with poor prognosis. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
