EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    2.3.1.180 | Anthrax |
18524602 |
Unsymmetric aryl-alkyl disulfide growth inhibitors of methicillin-resistant Staphylococcus aureus and Bacillus anthracis. |
causal interaction
therapeutic application
unassigned |
3
3
0 |
| 2.3.1.180 | Infections |
18524602 |
Unsymmetric aryl-alkyl disulfide growth inhibitors of methicillin-resistant Staphylococcus aureus and Bacillus anthracis. |
causal interaction
therapeutic application
unassigned |
3
3
0 |
| 2.3.1.180 | Tuberculosis |
10840036 |
Identification and substrate specificity of beta -ketoacyl (acyl carrier protein) synthase III (mtFabH) from Mycobacterium tuberculosis. |
therapeutic application
unassigned |
1
0 |
| 2.3.1.180 | Tuberculosis |
11278743 |
Crystal structure of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III. |
unassigned |
0 |
| 2.3.1.180 | Tuberculosis |
14552758 |
Biphenyl-based analogues of thiolactomycin, active against Mycobacterium tuberculosis mtFabH fatty acid condensing enzyme. |
ongoing research
therapeutic application
unassigned |
1
2
0 |
| 2.3.1.180 | Tuberculosis |
14698162 |
Acetylene-based analogues of thiolactomycin, active against Mycobacterium tuberculosis mtFabH fatty acid condensing enzyme. |
ongoing research
therapeutic application
unassigned |
1
2
0 |
| 2.3.1.180 | Tuberculosis |
15713483 |
Crystal structure of a substrate complex of Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III (FabH) with lauroyl-coenzyme A. |
ongoing research
therapeutic application
unassigned |
1
1
0 |
| 2.3.1.180 | Tuberculosis |
16040614 |
Probing the mechanism of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III mtFabH: factors influencing catalysis and substrate specificity. |
unassigned |
0 |
| 2.3.1.180 | Tuberculosis |
17189694 |
Synthesis and biological evaluation of thiazolidine-2-one 1,1-dioxide as inhibitors of Escherichia coli beta-ketoacyl-ACP-synthase III (FabH). |
therapeutic application
unassigned |
3
0 |
| 2.3.1.180 | Tuberculosis |
18096200 |
Probing reactivity and substrate specificity of both subunits of the dimeric Mycobacterium tuberculosis FabH using alkyl-CoA disulfide inhibitors and acyl-CoA substrates. |
unassigned |
0 |
