EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    2.1.1.45 | Abortion, Habitual |
31960387 |
Direct Reprogramming of Mouse Embryonic Fibroblasts to Induced Trophoblast Stem Cells. |
therapeutic application
unassigned |
1
0 |
| 2.1.1.45 | Abortion, Spontaneous |
15985285 |
Influence of combined methylenetetrahydrofolate reductase (MTHFR) and thymidylate synthase enhancer region (TSER) polymorphisms to plasma homocysteine levels in Korean patients with recurrent spontaneous abortion. |
causal interaction
diagnostic usage
unassigned |
4
2
0 |
| 2.1.1.45 | Abortion, Spontaneous |
18990369 |
Effect of methylenetetrahydrofolate reductase and thymidylate synthase enhancer region polymorphisms on the risk of idiopathic recurrent spontaneous abortion in a Korean population. |
causal interaction
diagnostic usage
unassigned |
3
1
0 |
| 2.1.1.45 | Acquired Immunodeficiency Syndrome |
10731418 |
The crystal structure of thymidylate synthase from Pneumocystis carinii reveals a fungal insert important for drug design. |
causal interaction
therapeutic application
unassigned |
4
1
0 |
| 2.1.1.45 | Adenocarcinoma |
1394217 |
Time dependence of DNA lesions and growth inhibition by ICI D1694, a new quinazoline antifolate thymidylate synthase inhibitor. |
ongoing research
unassigned |
1
0 |
| 2.1.1.45 | Adenocarcinoma |
1732043 |
Mutation(s) of the thymidylate synthase gene of human adenocarcinoma cells causes a thymidylate synthase-negative phenotype that can be attenuated by exogenous folates. |
ongoing research
unassigned |
2
0 |
| 2.1.1.45 | Adenocarcinoma |
2528057 |
Activity of thymidylate synthetase and its inhibition by 5-fluorouracil in highly enzyme-overproducing cells resistant to 10-propargyl-5,8-dideazafolate. |
ongoing research
therapeutic application
unassigned |
1
2
0 |
| 2.1.1.45 | Adenocarcinoma |
3167844 |
Mechanisms of innate resistance to thymidylate synthase inhibition after 5-fluorouracil. |
diagnostic usage
therapeutic application
unassigned |
3
2
0 |
| 2.1.1.45 | Adenocarcinoma |
6889511 |
The effect of derivatives of folic acid on the fluorodeoxyuridylate-thymidylate synthetase covalent complex in human colon xenografts. |
diagnostic usage
ongoing research
unassigned |
1
4
0 |
| 2.1.1.45 | Adenocarcinoma |
7226054 |
Thymidylate synthetase activity and fluorouracil sensitivity of human colonic cancer and normal mucosal tissue preparations. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
3
3
4
2 |
