EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
|---|
   2.7.11.22 | 0.0000003 |
- |
N-[(3R)-1-[4-[(5-fluoro-6,8-dimethyl-5,6-dihydroimidazo[1',5':1,2]pyrido[3,4-d]pyrimidin-2-yl)amino]phenyl]pyrrolidin-3-yl]acetamide |
with isozyme CDK2, IC50 above 0.0000003 mM |
691293 |
| 2.7.11.22 | 0.0000005 |
- |
N-(1-[4-[(5-fluoro-6,8-dimethyl-5,6-dihydroimidazo[1',5':1,2]pyrido[3,4-d]pyrimidin-2-yl)amino]phenyl]azetidin-3-yl)acetamide |
with isozyme CDK2 |
691293 |
| 2.7.11.22 | 0.0000007 |
- |
4-(6-amino-4-cyclohexylmethoxy-5-nitrosopyrimidin-2-ylamino)-N-(2-hydroxyethyl)benzenesulfonamide |
- |
694510 |
| 2.7.11.22 | 0.0000008 |
- |
4-(6-amino-4-cyclohexylmethoxy-5-nitrosopyrimidin-2-ylamino)-N-(2,3-dihydroxypropyl)-benzenesulfonamide |
- |
694510 |
| 2.7.11.22 | 0.000001 |
- |
1-methyl-8-[[1-(methylsulfonyl)piperidin-4-yl]amino]-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide |
pH 7.5, 30°C |
722908 |
| 2.7.11.22 | 0.000001 |
- |
1-methyl-8-[[1-(phenylcarbonyl)piperidin-4-yl]amino]-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide |
pH 7.5, 30°C |
722908 |
| 2.7.11.22 | 0.000001 |
- |
3-isopropyl-5-(2-hydroxy-2-methylpropyl)amino-7-[4-(2-pyridyl)benzyl]amino-1(2)H-pyrazolo[4,3-d]pyrimidine |
isoform CDK5, at pH 7.5, temperature not specified in the publication |
738159 |
| 2.7.11.22 | 0.000001 |
- |
4-(6-amino-4-cyclohexylmethoxy-5-nitrosopyrimidin-2-ylamino)-benzenesulfonamide |
- |
694510 |
| 2.7.11.22 | 0.000001 |
- |
N-(2-methoxyethyl)-4-([4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]pyrimidin-2-yl]amino)benzenesulfonamide |
with isozyme CDK2 |
691302 |
| 2.7.11.22 | 0.0000013 |
- |
4-[[4-amino-6-(cyclohexylmethoxy)-5-nitrosopyrimidin-2-yl]amino]-N-(2-hydroxypropyl)benzenesulfonamide |
with isozyme CDK2 |
694510 |
