EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
|---|
    1.8.1.9 | -999 |
- |
more |
black tea extract and theaflavins (mixture of theaflavin, theaflavin-3-monogallate, theaflavin-3'-monogallate and theaflavin-3,3'-digallate) inhibit the purified TrxR1 with IC50 44 mg/ml and 21 mg/ml, respectively |
696492 |
| 1.8.1.9 | 0.00000062 |
- |
trisodium [3,3',3''-(phosphanetriyl-kappaP)tribenzenesulfonato(3-)](pyrimidine-2-thiolato-kappaS)aurate(3-) |
isoform TrxR1, in 0.2 M Na/K phosphate buffer (pH 7.4), at 37°C |
711755 |
| 1.8.1.9 | 0.00000074 |
- |
auranofin |
isoform TrxR1, in 0.2 M Na/K phosphate buffer (pH 7.4), at 37°C |
711755 |
| 1.8.1.9 | 0.00000096 |
- |
(4-methylpyrimidine-2-thiolato-kappaS)(1,3,5-triaza-7-phosphatricyclo[3.3.1.13,7]decane-kappaP)gold |
isoform TrxR1, in 0.2 M Na/K phosphate buffer (pH 7.4), at 37°C |
711755 |
| 1.8.1.9 | 0.00000154 |
- |
(pyridine-2-thiolato-kappaS)[1,1'-(1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane-3,7-diyl-kappaP)diethanone]gold |
isoform TrxR1, in 0.2 M Na/K phosphate buffer (pH 7.4), at 37°C |
711755 |
| 1.8.1.9 | 0.00000155 |
- |
(4-methylpyrimidine-2-thiolato-kappaS)[1,1'-(1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane-3,7-diyl-kappaP)diethanone]gold |
isoform TrxR1, in 0.2 M Na/K phosphate buffer (pH 7.4), at 37°C |
711755 |
| 1.8.1.9 | 0.00000161 |
- |
(pyridine-2-thiolato-kappaS)(1,3,5-triaza-7-phosphatricyclo[3.3.1.13,7]decane-kappaP)gold |
isoform TrxR1, in 0.2 M Na/K phosphate buffer (pH 7.4), at 37°C |
711755 |
| 1.8.1.9 | 0.00000167 |
- |
trisodium (4,5-dihydro-1,3-thiazole-2-thiolato-kappaS2)[3,3',3''-(phosphanetriyl-kappaP)tribenzenesulfonato(3-)]aurate(3-) |
isoform TrxR1, in 0.2 M Na/K phosphate buffer (pH 7.4), at 37°C |
711755 |
| 1.8.1.9 | 0.00000192 |
- |
(pyrimidine-2-thiolato-kappaS)(1,3,5-triaza-7-phosphatricyclo[3.3.1.13,7]decane-kappaP)gold |
isoform TrxR1, in 0.2 M Na/K phosphate buffer (pH 7.4), at 37°C |
711755 |
| 1.8.1.9 | 0.00000245 |
- |
auranofin |
isoform TrxR2, in 0.2 M Na/K phosphate buffer (pH 7.4), at 37°C |
711755 |
