EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
6.3.2.60 | ATP + L-glutamate + an [amino-group carrier protein mutant E42R]-C-terminal-L-glutamate |
- |
Thermococcus kodakarensis |
ADP + phosphate + an [amino-group carrier protein mutant E42R]-C-terminal-gamma-(L-glutamyl)-L-glutamate |
- |
? |
6.3.2.60 | ATP + L-glutamate + an [amino-group carrier protein]-C-terminal-L-glutamate |
- |
Thermococcus kodakarensis |
ADP + phosphate + an [amino-group carrier protein]-C-terminal-gamma-(L-glutamyl)-L-glutamate |
- |
? |
6.3.2.60 | ATP + L-glutamate + an [amino-group carrier protein]-C-terminal-L-glutamate |
the amino-group carrier protein is LysW. Determination of the crystal structure of the LysX family protein from Thermococcus kodakarensis, which catalyzes the conjugation of LysW with either alpha-aminoadipate (AAA) or glutamate, in a complex with LysW-gamma-AAA. Residue Tyr175 in TkLysX/ArgX plays a critical role in the recognition of glutamate |
Thermococcus kodakarensis |
ADP + phosphate + an [amino-group carrier protein]-C-terminal-gamma-(L-glutamyl)-L-glutamate |
- |
? |
6.3.2.60 | ATP + L-glutamate + [LysW]-C-terminal-L-glutamate |
- |
Sulfolobus acidocaldarius |
ADP + phosphate + [LysW]-C-terminal-gamma-(L-glutamyl)-L-glutamate |
- |
? |
6.3.2.60 | ATP + L-glutamate + [LysW]-C-terminal-L-glutamate |
- |
Sulfolobus acidocaldarius DSM 639 |
ADP + phosphate + [LysW]-C-terminal-gamma-(L-glutamyl)-L-glutamate |
- |
? |
6.3.2.60 | ATP + L-glutamate + [LysW]-C-terminal-L-glutamate |
- |
Sulfolobus acidocaldarius ATCC 33909 |
ADP + phosphate + [LysW]-C-terminal-gamma-(L-glutamyl)-L-glutamate |
- |
? |
6.3.2.60 | ATP + L-glutamate + [LysW]-C-terminal-L-glutamate |
- |
Sulfolobus acidocaldarius NBRC 15157 |
ADP + phosphate + [LysW]-C-terminal-gamma-(L-glutamyl)-L-glutamate |
- |
? |
6.3.2.60 | ATP + L-glutamate + [LysW]-C-terminal-L-glutamate |
- |
Sulfolobus acidocaldarius NCIMB 11770 |
ADP + phosphate + [LysW]-C-terminal-gamma-(L-glutamyl)-L-glutamate |
- |
? |
6.3.2.60 | ATP + L-glutamate + [LysW]-C-terminal-L-glutamate |
- |
Sulfolobus acidocaldarius JCM 8929 |
ADP + phosphate + [LysW]-C-terminal-gamma-(L-glutamyl)-L-glutamate |
- |
? |
6.3.2.60 | more |
purified recombinant TK0278 recognizes alpha-aminoadipate (AAA) and glutamate as substrates and ligated both compounds with TK0279, an amino group carrier protein LysW in this microorganism, in an ATP-dependent manner |
Thermococcus kodakarensis |
? |
- |
- |