EC Number   |
General Information |
Reference |
|---|
    4.3.3.7 | malfunction |
enzyme mutants with deleted dapA gene are viable and able to grow in a mouse lung infection model |
720852 |
| 4.3.3.7 | malfunction |
the FaDHDPS1 deletion mutant is defective in conidiation, virulence and deoxynivalenol biosynthesis. In addition, deletion of FaDHDPS1 results in tolerance to sodium pyruvate, lysine, low temperature and Congo red |
747420 |
| 4.3.3.7 | metabolism |
DHDPS is an oligomeric enzyme that catalyzes the first committed step of the lysine biosynthesis pathway in plants and bacteria, which yields essential building blocks for cell-wall and protein synthesis |
-, 713631 |
| 4.3.3.7 | metabolism |
dihydrodipicolinate synthase is a key enzyme in the lysine biosynthesis pathway that catalyzes the condensation of pyruvate and aspartate semi-aldehyde |
729385 |
| 4.3.3.7 | metabolism |
feedback regulation of the enzyme is directly correlated to L-lysine production |
-, 729062 |
| 4.3.3.7 | metabolism |
first enzyme unique to the diaminopimelate pathway of lysine biosynthesis |
718827 |
| 4.3.3.7 | metabolism |
lysine biosynthesis in plants is tightly regulated by feedback inhibition of the end product on dihydrodipicolinate synthase, the first enzyme of the lysine-specific branch |
-, 730623, 730624 |
| 4.3.3.7 | metabolism |
sequential production of dihydrodipicolinate and dipicolinic acid appears to be catalysed by DHDPA synthase followed by an electron transfer flavoprotein, EtfA from Clostridium perfringens. Spontaneous dipicolinic acid formation in the presence of high concentrations of DapA |
705792 |
| 4.3.3.7 | metabolism |
the enzyme catalyses the first committed step in the lysine biosynthesis pathway, the condensation of pyruvate and (S)-aspartate semialdehyde to form (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid |
-, 730915 |
| 4.3.3.7 | metabolism |
the enzyme catalyses the first committed step in the lysine biosynthesis pathway, the condensation of pyruvate and (S)-aspartate semialdehyde to form (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid |
-, 728891, 728904, 729694, 730908 |
