EC Number   |
General Information |
Reference |
|---|
   2.7.11.24 | evolution |
C493C.10 is an orthologue of mammalian JNK |
740759 |
| 2.7.11.24 | evolution |
jnk-1 is an orthologue of mammalian JNK |
740759 |
| 2.7.11.24 | evolution |
kgb-1 is an orthologue of mammalian JNK |
740759 |
| 2.7.11.24 | evolution |
kgb-2 is an orthologue of mammalian JNK. The JNK homologue KGB-2 shows 84% identity with KGB-1 |
740759 |
| 2.7.11.24 | evolution |
pmk-1 is an orthologue of mammalian p38. The three pmk genes pmk1, pmk-2, and pmk-3, are encoded by a single polycistronic transcript (operon), precluding the generation of double mutants by traditional genetic crosses |
740759 |
| 2.7.11.24 | evolution |
pmk-2 is an orthologue of mammalian p38. The three pmk genes pmk1, pmk-2, and pmk-3, are encoded by a single polycistronic transcript (operon), precluding the generation of double mutants by traditional genetic crosses |
740759 |
| 2.7.11.24 | evolution |
pmk-3 is an orthologue of mammalian p38. The three pmk genes pmk1, pmk-2, and pmk-3, are encoded by a single polycistronic transcript (operon), precluding the generation of double mutants by traditional genetic crosses |
740759 |
| 2.7.11.24 | evolution |
the enzyme contains the conserved catalytic domain of the serine/threonine kinases |
-, 741233 |
| 2.7.11.24 | malfunction |
a kgb-1 null mutant, obtained by targeted deletion, shows extra germ cells, increased number of P granules, and temperature-sensitive sterility. RNAi-mediated knockdown of glh-1 in kgb-1 mutants partially rescues the P granule number and temperature-sensitive sterility. Null mutations in vhp-1 cause larval lethality, which can be suppressed by null mutations in mlk-1, mek-1, kgb-1, dlk-1, or pmk-3 |
740759 |
| 2.7.11.24 | malfunction |
enzyme inhibition can counteract triptolide-induced apoptosis |
762008 |
