EC Number |
General Information |
Reference |
---|
2.5.1.18 | evolution |
glutathione transferase classes alpha, pi, and mu and their GSH activation mechanism, overview |
723041 |
2.5.1.18 | evolution |
GST5118 belongs to a distinct class named GSTFuA, for fungal specific GST class A, as part of the GST superfamily |
722794 |
2.5.1.18 | evolution |
kappa class GSTs are a distinct class of the GST superfamily or Trx (thioredoxin)-fold superfamily because of their unique cellular localization, function and structure. GSTks do not contain a conserved CXXC motif at the active site |
721532 |
2.5.1.18 | evolution |
structures and properties of YghU and YfcG indicate that they are members of the same distinct subfamily of GSH transferase homologues, proposed to be called the Nu-class GSH transferases. Cytoscape cluster analysis of the GSH transferase superfamily, overvew |
721631 |
2.5.1.18 | evolution |
TDR1 belongs to the glutathione-S-transferase (GST) superfamily |
723649 |
2.5.1.18 | evolution |
the cytosolic glutathione transferases, GSTs, comprise a super family of proteins that can be categorized into multiple classes with a mixture of highly specific and overlapping functions |
721739 |
2.5.1.18 | evolution |
the cytosolic glutathione transferases, GSTs, comprise a superfamily of proteins that can be categorized into multiple classes with a mixture of highly specific and overlapping functions |
721739 |
2.5.1.18 | evolution |
the enzyme belongs to the glutathione transferase, GST, superfamily. Phylogenetic analysis shows, among the Delta class, GSTD1 and GSTD10 appear to be recently diverged transcripts with 86% amino acid sequence similarity |
721434 |
2.5.1.18 | evolution |
the enzyme belongs to the soluble plant GST superfamily of dimeric enzymes, isozymes classes, overview. Dehydroascorbate reductase and tetrachlorohydroquinone dehalogenase-like proteins also belong to the GST superfamily |
723365 |
2.5.1.18 | malfunction |
a single SNP causing an I71L substitution in African subjects causes diminished activity with several substrates including CDNB and 7-chloro-4-nitrobenz-2-oxa-1,3-diazole as a result of an elevation in its Km for GSH, but the specific activity towards DELTA5-androsten-3,17-dione and the Km GSH of the L71 variant are not changed |
721739 |