EC Number   |
Expression |
Reference |
|---|
    3.1.4.4 | down |
PLD is suppressed in endothelial cell senescence |
709924 |
| 3.1.4.4 | down |
triptolide, a natural, biologically active compound as a diterpenoid triepoxide originally purified from the Chinese herb Tripterygium wilfordii, induces suppression of phospholipase D expression, inhibits proliferation of MDA-MB-231 breast cancer cells and significantly inhibits PLD promoter activity in cells expressing the PLD promoters both PLD isozymes with similar inhibitory potency, triptolide decreases both basal and phorbol 12-myristate 13-acetate-induced PLD activation, overview |
708430 |
| 3.1.4.4 | up |
abscisic acid enhances the PLDzeta2 promoter activity in root caps |
710334 |
| 3.1.4.4 | up |
an increase in PLD2 expression correlates with an enhanced ERK-1/-2 activation following PMA/ionomycin stimulation |
707543 |
| 3.1.4.4 | up |
phorbol 12-myristate 13-acetate, PMA, as a tumor promoter enhances PLD1 expression via NFkappaB-dependent signaling pathway and increases cell proliferation and invasion |
708430 |
| 3.1.4.4 | up |
PLD1 expression is induced by high glucose levels |
714923 |
