EC Number   |
Natural Substrates |
|---|
   4.6.1.25 | a [pre-mRNA]-containing guanosine-adenosine + H2O |
the enzyme controls the expression of a number of phage early genes. It cleaves early mRNAs between Ap and Gp at one specific GpGpApGp site |
| 4.6.1.25 | a [pre-mRNA]-containing guanosine-adenosine + H2O |
the enzyme is necessary for the degradation of early but not middle or late mRNAs. The synthesis of several early proteins is down-regulated, probably as a consequence of RegB cleavages in the Shine-Dalgarno sequence of these genes. The synthesis of several other proteins is up-regulated, suggesting that processing by RegB might improve translation by changing the conformation of a transcript |
| 4.6.1.25 | a [pre-mRNA]-containing guanosine-adenosine + H2O |
the enzyme participates in the bacteriophage T4 life cycle by favoring early messenger RNA breakdown. It specifically cleaves GGAG sequences found in intergenic regions, mainly in translation initiation sites |
| 4.6.1.25 | a [pre-mRNA]-containing guanosine-adenosine + H2O |
- |
