EC Number   |
Natural Substrates |
|---|
    2.5.1.18 | 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane + glutathione |
detoxification of the insecticide DDT, especially by isozyme agGSTe2 |
| 2.5.1.18 | 12-oxo-phytodienoic acid + glutathione |
- |
| 2.5.1.18 | 2-hydroxychromene-2-carboxylic acid |
HCCA isomerase catalyzes the glutathione-dependent interconversion of 2-hydroxychromene-2-carboxylic acid and trans-o-hydroxybenzylidene pyruvic acid in the naphthalene catabolic pathway of Pseudomonas putida, mechanisms in the naphthalene catabolic pathwayoverview |
| 2.5.1.18 | brostallicin + glutathione |
involved in activation of the prodrug, mechanism, overview. The reaction proceeds via the alpha-chloroamido derivative of the GSH-brostallicin adduct, is able to alkylate DNA in a sequence-specific manner and appears to be the active form of the drug, brostallicin cytotoxicity of brostallicin is higher in cells overexpressing either the GST-pi or the GST-mu gene |
| 2.5.1.18 | glutathione + (2E,4Z)-5-chloro-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid |
- |
| 2.5.1.18 | glutathione + (2Z,4E)-3-chloro-2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid |
- |
| 2.5.1.18 | glutathione + (2Z,4E)-3-chloro-6-(3,5-dichlorophenyl)-2-hydroxy-6-oxohexa-2,4-dienoic acid |
- |
| 2.5.1.18 | glutathione + 1-chloro-2,4-dinitrobenzene |
- |
| 2.5.1.18 | glutathione + 1-chloro-2,4-dinitrobenzene |
the catalytic activity of purified GST from Nanyang city population with GSH is much higher than the activity of the enzyme from other populations, while the Wuzhou population reaches the highest in Vmax for substrate 1-chloro-2,4-dinitrobenzene |
| 2.5.1.18 | glutathione + alachlor |
isozyme GSTI |
