EC Number |
Metals/Ions |
Reference |
---|
6.3.1.2 | 2-oxoglutarate |
directly stimulates activity |
728318 |
6.3.1.2 | Al3+ |
results in 8.91tivity compared to Mg2+ |
745741 |
6.3.1.2 | Ba2+ |
increases the activity of wild-type and mutant enzymes at 1 mM |
744127 |
6.3.1.2 | Ca2+ |
can partially substitute for Mg2+ |
745708 |
6.3.1.2 | Ca2+ |
can substitute for Mg2+ in biosynthesis of glutamine with 30% of the efficiency obtained with Mg2+ |
662044 |
6.3.1.2 | Ca2+ |
results in 43.9% activity compared to Mg2+ |
745741 |
6.3.1.2 | Ca2+ |
stimulates activity at 1 mM |
673742 |
6.3.1.2 | Cd2+ |
0.5 mM, activity rises by 96% |
671178 |
6.3.1.2 | Cd2+ |
activates enzyme form EII more than EI |
37507 |
6.3.1.2 | Cl- |
chloride stimulates the production of active enzyme by about 300%, in the absence of chloride in the assay buffer, glutamine synthetase activity is decreased by as much as 90% |
674303 |