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EC Number
Inhibitors
Commentary
Structure
5.5.1.2
citrate
noncompetitive, localization of binding pocket on the enzyme outside the active site
5.5.1.2
CoCl2
-
5.5.1.2
CuCl2
-
5.5.1.2
Dicarboxylic acids
saturated dicarboxylic acids with the exception of oxalate, are less inhibitory as the molecular weight increases. Compounds with two cis-carboxyl groups are much more inhibitory than the corresponding trans-isomers
5.5.1.2
EDTA
the enzyme is partially sensitive to EDTA
5.5.1.2
isocitrate
noncompetitive, localization of binding pocket on the enzyme outside the active site
5.5.1.2
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enzyme shows significantly reduced activities in sodium/potassium phosphate/citrate buffers
5.5.1.2
NiCl2
-
5.5.1.2
phosphate
-
5.5.1.2
Tricarboxylic acids
-
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