EC Number |
Inhibitors |
Structure |
---|
2.7.4.6 | 8-bromo-IDP |
in excess |
|
2.7.4.6 | Ag2+ |
- |
|
2.7.4.6 | AMP |
kinetics, substrate inhibition |
|
2.7.4.6 | AMP |
IC50: 1.9 mM |
|
2.7.4.6 | ATP |
inhibition of nuclease activity |
|
2.7.4.6 | Ca2+ |
above 5 mM |
|
2.7.4.6 | cAMP |
IC50 6 mM, weak, competitive |
|
2.7.4.6 | cAMP |
IC50: 26.7 mM |
|
2.7.4.6 | cAMP |
decreases the reaction speed of NDPK1 proportionally to the ligand concentration. Addition of 0.1 mM, 0.2 mM, and 0.5 mM cAMP reduces the specific activity of NDPK1 to 96%, 91%, and 84%, respectively, of the control |
|
2.7.4.6 | cGMP |
decreases the reaction speed of NDPK1 proportionally to the ligand concentration. Addition of 0.1 mM, 0.2 mM, and 0.5 mM cGMP reduces the reaction speed to 84%, 69%, and 51% of the control |
|