EC Number   |
Activating Compound |
Reference |
|---|
   3.1.4.11 | (2-{4-methoxy-3,5-bis-[2-methoxy-5-(2-methylamino-ethyl)-benzyl]-phenyl}-ethyl)-methyl amine |
compound 48/80 i.e. (2-{4-methoxy-3,5-bis-[2-methoxy-5-(2-methylamino-ethyl)-benzyl]-phenyl}-ethyl)-methyl amine, CAS REG. NO.: 94724-12-6, the calmodulin antagonists activate at least one form of the rod outer segment enzyme by a calmodulin-independent mechanism |
135135 |
| 3.1.4.11 | 2-nonenal |
at 1-100 nM: activates PL-C in DMSO-differentiated HL-60 cells, at 1-10 nM: activates PL-C in undifferentiated HL-60 cells |
650786 |
| 3.1.4.11 | 4-hydroxynonenal |
at 10-1000 nM, activates PL-C in both undifferentiated and DMSO-differentiated HL-60 cells |
650786 |
| 3.1.4.11 | activated Galpha proteins |
- |
716560 |
| 3.1.4.11 | albumin |
maximal activation of hydrolysis of phosphatidylinositol 4,5-diphosphate at 0.0125 mg/ml |
135136 |
| 3.1.4.11 | arachidonic acid |
enhances hyrolysis of phosphatidylinositol 4,5-diphosphate, membrane bound enzyme and cytosolic enzyme |
135123 |
| 3.1.4.11 | ARGHAP6 |
a GTPase-activating protein for RhoA. Activates PLC-gamma1 and increases the Vmax of PLC-beta1 and enhances its response to Ca2+ stimulation. ARHGAP6 protein binds to and up-regulates PLC-beta1 both under in vitro and in vivo conditions |
692640 |
| 3.1.4.11 | B cell antigen receptor |
induces activation of PLC-gamma2, pathway |
649330 |
| 3.1.4.11 | beta-estradiol |
- |
680080 |
| 3.1.4.11 | Ca2+ |
requirement |
649088 |
