EC Number |
Activating Compound |
Reference |
---|
3.1.1.4 | 12-O-tetradecanoylphorbol-13-acetate |
a protein kinase C agonist, has no effect on Prdx6 expression but leads to about 75% increase in aiPLA2 activity |
690843 |
3.1.1.4 | 3,5-Dibromosalicylate |
enhanced enzyme penetration, activation above the normal cutoff pressure of PLA2 |
133911 |
3.1.1.4 | 3,5-diiodosalicylate |
enhanced enzyme penetration, activation above the normal cutoff pressure of PLA2 |
133911 |
3.1.1.4 | Acetyl salicylate |
enhanced enzyme penetration, activation above the normal cutoff pressure of PLA2 |
133911 |
3.1.1.4 | Acylating agents |
example: fatty acid imidazolides |
133907 |
3.1.1.4 | ADP |
stimulation, presence promotes oligomerisation of enzyme |
729999 |
3.1.1.4 | ATP |
- |
133876 |
3.1.1.4 | ATP |
addition of ATP and ADP promote oligomerization of the isozyme, which probably underlies the stimulatory effect of nucleotides on its activity. ATP hydrolysis is not required to promote isozyme IPLA-1 lipase activity in vitro |
729999 |
3.1.1.4 | ATP |
cellular GIVA PLA2 activity is induced by the treatment of cells with Ca+2 mobilizing agonists, such as the purinergic P2X7 receptor agonist ATP |
691109 |
3.1.1.4 | ATP |
plasmalogen-specific PLA2, activating |
133875 |