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Gene ontology
Version 2014-12-22
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Details for class II DNA-(apurinic or apyrimidinic site) endonuclease activity
Gene ontology ID
GO:0052720
Definition
Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a deoxyribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends
Comment
Class II AP endonuclease is a nuclease, but not Class I, III and IV.
Synonyms
1. class II DNA-(apurinic or apyrimidinic site) lyase activity
References
1. PMID 19401441
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