Literature summary for 6.3.2.2 extracted from

Chen, C.N.; Brown-Borg, H.M.; Rakoczy, S.G.; Ferrington, D.A.; Thompson, L.V.
Aging impairs the expression of the catalytic subunit of glutamate cysteine ligase in soleus muscle under stress (2010), J. Gerontol. A Biol. Sci. Med. Sci., 65, 129-137.

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Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
soleus	-	Rattus norvegicus	-

General Information

General Information	Comment	Organism
metabolism	the regulation of GCL, especially the catalytic subunit, with stress may be compromised in aging muscles. In aging muscles with 14 days of hind-limb unloading, failure to maintain the accelerated GCL catalytic subunit production and GCL activity, are associated with the GSH depletion	Rattus norvegicus

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Release 2023.1 (January 2023)