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Literature summary for 6.2.1.3 extracted from

  • Day, J.C.; Goodall, T.I.; Bailey, M.J.
    The evolution of the adenylate-forming protein family in beetles: Multiple luciferase gene paralogues in fireflies and glow-worms (2008), Mol. Phylogenet. Evol., 50, 93-101.
    View publication on PubMed
Search for more literature for 6.2.1.3

Cloned(Commentary)

Cloned (Comment) Organism
DNA and amino acid sequence determination and analysis, phylogenetic analysis, luciferase-like paralogues are located in close proximity on a chromosome, overview Tribolium castaneum
DNA and amino acid sequence determination and analysis, phylogenetic analysis, overview Photinus pyralis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Photinus pyralis firefly luciferase has two catalytic functions, it can act as a monooxygenase, luciferase, EC 1.13.12.7, but can also synthesize a long-chain fatty acyl-CoA from various long-chain fatty acids in the presence of ATP, CoA and Mg2+ ?
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 ?
additional information Tribolium castaneum luciferase shows beetle luciferase may have arisen from a process of subfunctionalization as opposed to neofunctionalization early on in the evolution of the Elateroidea ?
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 ?

Organism

Organism UniProt Comment Textmining
Photinus pyralis P08659 North American firefly
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Tribolium castaneum
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 red flour beetle
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information firefly luciferase has two catalytic functions, it can act as a monooxygenase, luciferase, EC 1.13.12.7, but can also synthesize a long-chain fatty acyl-CoA from various long-chain fatty acids in the presence of ATP, CoA and Mg2+ Photinus pyralis ?
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 ?
additional information luciferase shows beetle luciferase may have arisen from a process of subfunctionalization as opposed to neofunctionalization early on in the evolution of the Elateroidea Tribolium castaneum ?
-
 ?

Synonyms

Synonyms Comment Organism
fatty acyl-CoA synthetase
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 Tribolium castaneum
fatty acyl-CoA synthetase
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 Photinus pyralis
luciferase-like protein
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 Tribolium castaneum
luciferase-like protein
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 Photinus pyralis
More the enzyme is a part of a larger AMP-forming superfamily Tribolium castaneum
More the enzyme is a part of a larger AMP-forming superfamily Photinus pyralis
PhpLL1
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 Photinus pyralis