Application | Comment | Organism |
---|---|---|
medicine | anticonvulsants valnoctamide and valrocemide drastically reduce enzyme activity in crude brain homogenate | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
valnoctamide | valproate derivative with anticonvulsant effect. Drastic inhibition of enzyme at 1 mM in crude brain homogenate, competitive | Homo sapiens | |
valrocemide | valproate derivative with anticonvulsant effect. Drastic inhibition of enzyme at 1 mM in crude brain homogenate | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.8 | - |
D-glucose 6-phosphate | pH 7.6, 37°C | Homo sapiens | |
3.4 | - |
D-glucose 6-phosphate | presence of 0.6 mM valnoctamide, pH 7.6, 37°C | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glucose 6-phosphate | - |
Homo sapiens | 1D-myo-inositol 3-phosphate | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.18 | - |
valnoctamide | pH 7.6, 37°C | Homo sapiens |