Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1(omega-Carboxylalkyl)imidazoles | very potent | Homo sapiens | |
1-Methyl imidazole | - |
Homo sapiens | |
2-Isopropyl-3-nicotinylindole | - |
Homo sapiens | |
4-{2-[(4-chlorophenyl)methyl]-3-phenylpropanoyl}phenyl hydrogen benzylphosphonate | i.e. N-0164 | Homo sapiens | |
9,11(Epoxymethano) prostanoic acid | - |
Homo sapiens | |
9,11-Azo-15-hydroxyprosta-5,13-dienoic acid | - |
Homo sapiens | |
9,11-Azoprosta-5,13-dienoic acid | - |
Homo sapiens | |
9,11-Epoxymethano-15-hydroxy-prosta-5,13-dienoic acid | - |
Homo sapiens | |
Benzydamine | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Homo sapiens | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
platelet | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 prostaglandin G2 + H2O | i.e. PGG2 | Homo sapiens | 15-hydroperoxythromboxane B2 + 12-hydroperoxy-5,8,10-heptadecatrienoic acid | - |
? | |
prostaglandin H1 | - |
Homo sapiens | 12(L)-hydroxy-8,10-heptadecadienoic acid + thromboxane B1 | thromboxane B1 is scarcely detectable, the major product is 12(L)-hydroxy-8,10-heptadecadienoic acid | ? | |
Prostaglandin H2 | i.e. PGH2 | Homo sapiens | thromboxane B2 + 12(L)-hydroxy-5,8,10-heptadecatrienoic acid | the thromboxane A2 that is formed by the enzyme is transformed to thromboxane B2 | ? | |
Prostaglandin H2 | i.e. PGH2 | Homo sapiens | thromboxane B2 + 12(L)-hydroxy-5,8,10-heptadecatrienoic acid | + malondialdehyde | ? | |
Prostaglandin H2 | i.e. PGH2 | Homo sapiens | thromboxane B2 + 12(L)-hydroxy-5,8,10-heptadecatrienoic acid | the ratio of thromboxane to C17 hydroxyfatty acid formation is 1:1 | ? |