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Literature summary for 4.3.1.4 extracted from
- Formiminotransferase-cyclodeaminase: a bifunctional enzyme from porcine liver (1980), Methods Enzymol., 66, 626-630.
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| formiminotransferase-cyclodeaminase enzyme complex | Sus scrofa |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.026 | - |
5-formiminotetrahydrofolate | in the presence of KCl | Sus scrofa |  |
| 0.175 | - |
5-formiminotetrahydrofolate | - |
Sus scrofa | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| K+ | activates | Sus scrofa | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 5-formiminotetrahydrofolate | Sus scrofa | - |
? | - |
? | |
| additional information | Sus scrofa | folate-dependent bifunctional enzyme formiminoglutamate: tetrahydrofolate formiminotransferase-formiminotetrahydrofolate cyclodeaminase catalyzes two sequential reactions of the histidine degradation pathway | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sus scrofa | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| formiminotransferase-cyclodeaminase enzyme complex | Sus scrofa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Sus scrofa | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Sus scrofa |
| 25 | - |
- |
Sus scrofa |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 5-formiminotetrahydrofolate | - |
Sus scrofa | 5,10-methenyltetrahydrofolate + NH3 | - |
r | |
| 5-formiminotetrahydrofolate | - |
Sus scrofa | ? | - |
? | |
| additional information | folate-dependent bifunctional enzyme formiminoglutamate: tetrahydrofolate formiminotransferase-formiminotetrahydrofolate cyclodeaminase catalyzes two sequential reactions of the histidine degradation pathway | Sus scrofa | ? | - |
? | |
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