Literature summary for 4.3.1.24 extracted from

Zon, J.; Amrhein, N.; Gancarz, R.
Inhibitors of phenylalanine ammonia-lyase: 1-aminobenzylphosphonic acids substituted in the benzene ring (2002), Phytochemistry, 59, 9-21.

Search for more literature for 4.3.1.24

Inhibitors

Inhibitors	Comment	Organism	Structure
(+)-1-amino-3',4'-dichlorobenzylphosphonic acid	strongest inhibitor among 1-aminobenzylphosphonic acids	Fagopyrum esculentum
(+-)-2-aminooxy-3-phenylpropanoic acid	strong inhibition	Fagopyrum esculentum
(R)-1-amino-2-phenylwthylphosphonic acid	strong inhibition	Fagopyrum esculentum
1-aminobenzylphosphonic acid	various substitutes in the benzene ring	Fagopyrum esculentum
2-aminoindan-2-phosphonic acid	-	Fagopyrum esculentum

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
L-phenylalanine	Fagopyrum esculentum	-	(E)-cinnamate + NH3	-	r

Organism

Organism	UniProt	Comment	Textmining
Fagopyrum esculentum	-	buckwheat	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-phenylalanine	-	Fagopyrum esculentum	(E)-cinnamate + NH3	-	?
L-phenylalanine	-	Fagopyrum esculentum	(E)-cinnamate + NH3	-	r

Synonyms

Synonyms	Comment	Organism
PAL	-	Fagopyrum esculentum

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.00008	-	(+)-1-amino-3',4'-dichlorobenzylphosphonic acid	-	Fagopyrum esculentum

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Release 2023.1 (January 2023)