Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
beta-myrcene + H2O | Castellaniella defragrans | - |
(3S)-linalool | - |
? | |
beta-myrcene + H2O | Castellaniella defragrans 65Phen | - |
(3S)-linalool | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Castellaniella defragrans | E1XUJ2 | i.e. Alcaligenes defragrans, gene ldi | - |
Castellaniella defragrans 65Phen | E1XUJ2 | i.e. Alcaligenes defragrans, gene ldi | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
beta-myrcene + H2O | - |
Castellaniella defragrans | (3S)-linalool | - |
? | |
beta-myrcene + H2O | stereospecific reaction, introduction of the hydroxy group on the si-face of beta-myrcene | Castellaniella defragrans | (3S)-linalool | (3S)-linalool is formed with an enantiomeric excess of at least 95.4%, (3R)-inalool is not detected | ? | |
beta-myrcene + H2O | - |
Castellaniella defragrans 65Phen | (3S)-linalool | - |
? | |
beta-myrcene + H2O | stereospecific reaction, introduction of the hydroxy group on the si-face of beta-myrcene | Castellaniella defragrans 65Phen | (3S)-linalool | (3S)-linalool is formed with an enantiomeric excess of at least 95.4%, (3R)-inalool is not detected | ? | |
additional information | the thermodynamically favoured direction is the isomerization of geraniol to linalool and the dehydration reaction to beta-myrcene | Castellaniella defragrans | ? | - |
? | |
additional information | the thermodynamically favoured direction is the isomerization of geraniol to linalool and the dehydration reaction to beta-myrcene | Castellaniella defragrans 65Phen | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
LDI | - |
Castellaniella defragrans |
ldi/LDI | - |
Castellaniella defragrans |
linalool dehydratase-isomerase | - |
Castellaniella defragrans |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Castellaniella defragrans |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
9 | - |
assay at | Castellaniella defragrans |
General Information | Comment | Organism |
---|---|---|
metabolism | the bifunctional linalool dehydratase-isomerase ldi/LDI is the initial enzyme in the anaerobic beta-myrcene degradation pathway and catalyzes the hydration of beta-myrcene to (S)-(+)-linalool and its isomerization to geraniol. A high-affinity geraniol dehydrogenase geoA/GeDH and a geranial dehydrogenase geoB/GaDH contribute to the formation of geranic acid | Castellaniella defragrans |