Any feedback?
Literature summary for 3.5.1.99 extracted from
- 1-Heteroaryl-3-phenoxypropan-2-ones as inhibitors of cytosolic phospholipase A2alpha and fatty acid amide hydrolase Effect of the replacement of the ether oxygen with sulfur and nitrogen moieties on enzyme inhibition and metabolic stability (2015), Bioorg. Med. Chem., 23, 2579-2592 .
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1-(1H-benzotriazol-1-yl)-3-(4-phenoxyphenoxy)propan-2-one | - |
Rattus norvegicus |  |
| 1-(1H-benzotriazol-1-yl)-3-[(4-phenoxyphenyl)thio]propan-2-one | - |
Rattus norvegicus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | P97612 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| FAAH | - |
Rattus norvegicus |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.000024 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 1-(1H-benzotriazol-1-yl)-3-(4-phenoxyphenoxy)propan-2-one | |
| 0.0016 | - |
pH and temperature not specified in the publication | Rattus norvegicus | 1-(1H-benzotriazol-1-yl)-3-[(4-phenoxyphenyl)thio]propan-2-one | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
