Application | Comment | Organism |
---|---|---|
medicine | possible target for new broad spectrum antimicrobial agents | Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(RS)- and (SR)-3-[(RS)-benzenesulfinyl]heptanoic acid hydroxyamide | mixture of both components, IC50: 0.0001 mM, possible antimicrobial agent | Escherichia coli | |
(RS)-3-(phenylsulfonyl)heptanoic acid hydroxyamide | IC50: 0.035 micro molar, possible antimicrobial agent | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cell culture | - |
Escherichia coli | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-formyl-Met-Ala-Ser + H2O | - |
Escherichia coli | formate + Met-Ala-Ser | - |
? |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000035 | - |
IC50: 0.035 micro molar, possible antimicrobial agent | Escherichia coli | (RS)-3-(phenylsulfonyl)heptanoic acid hydroxyamide | |
0.0001 | - |
mixture of both components, IC50: 0.0001 mM, possible antimicrobial agent | Escherichia coli | (RS)- and (SR)-3-[(RS)-benzenesulfinyl]heptanoic acid hydroxyamide |