Literature summary for 3.4.24.B6 extracted from

Yamazaki, H.; Tran, B.; Beniash, E.; Kwak, S.Y.; Margolis, H.C.
Proteolysis by MMP20 prevents aberrant mineralization in secretory enamel (2019), J. Dent. Res., 98, 468-475 .

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Organism

Organism	UniProt	Comment	Textmining
Mus musculus	P57748	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

General Information

General Information	Comment	Organism
physiological function	characteristic rod structures observed in wild-type enamel exhibit amorphous features in newly deposited enamel, which subsequently transform into apatite-like crystals in older enamel. Initial mineral formation in Mmp20-null enamel proceeds in the same manner as in the wild-type, but soon after a rod structure begins to form, large plate-like crystals appear randomly within the developing Mmp20-null enamel layer. As development continues, these plate-like crystals become dominant and obscure the appearance of the enamel rod structure. Then the Mmp20-null enamel layer stopps growing in thickness. Mmp20-null enamel contains a significant portion of octacalcium phosphate, unlike wild-type enamel	Mus musculus

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Release 2023.1 (January 2023)