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aggrecan + H2O
?
cleavage site is Asn341-Phe342
-
?
ameloblastin + H2O
ameloblastin fragments
amelogenin + H2O
23 kDa amelogenin + 5 kDa tyrosine-rich amelogenin peptide
cleaves amelogenin between Trp45 and Leu46
-
-
?
amelogenin + H2O
amelogenin fragment P148
-
-
-
?
amelogenin + H2O
amelogenin fragments
amelogenin + H2O
amelogenin fragments rH163 + rH146
-
in high phosphates conditions (20.9 mM KH2PO4) no cleavage site is observed in the central region of residues Q54P146, which also shows the slowest cleavage rate with the maximum accumulation of fragment rH163 at 4 h time-point. In the no calcium and phosphates conditions, the accumulation of rH163 reaches the maximum amount at 1 h and the cleavage in the central region Q54-P146 appears only after 5 h. Under high calcium conditions (33.4 mM CaCl2), the fastest cleavage rate is observed and also few exclusive and additional cleavage sites at T61, H67. Other conditions also show some exclusive cleavage sites such as P2 for no calcium and phosphates, P50 for low calcium and phosphates and G10 for high calcium and phosphates. The N-terminal positions Y11, N13, F14, S15, E17, K23, W24, P33, G42, and S53 and the C-terminal positions P155 and T158 are cleaved in all conditions used
-
?
amelogenin + H2O
fragments of amelogenin
-
-
-
-
?
amylogenin + H2O
4 major peptide fragments of MWs 24 kDa, 23 kDa, 22 kDa, and 20 kDa
-
-
?
cartilage oligomeric matrix protein + H2O
60 kDa protein
100 kDa protein substrate
-
?
dentin sialophosphoprotein + H2O
dentin sialoprotein-glycoprotein + dentin phosphoprotein
-
-
-
-
?
dentin sialoprotein-glycoprotein + H2O
dentin sialoprotein + dentin glycoprotein
-
-
-
-
?
E-cadherin + H2O
?
-
MMP20 cleaves the extracellular domain of E-cadherin
-
-
?
enamel protein + H2O
?
MMP-20 is secreted along with enamel proteins by secretory stage ameloblasts into the enamel matrix of developing teeth. Enamel protein cleavage products accumulate in the space between the crystal ribbons, helping to support them. MMP-20 steadily cleaves accumulated enamel proteins, so their concentration decreases with depth. The principle functions of MMP-20 in dental enamel formation is to facilitate the orderly replacement of organic matrix with mineral, generating an enamel layer that is harder, less porous, and unstained by retained enamel proteins
-
-
?
enamelin + H2O
enamelin fragments
-
-
-
-
?
endostatin + H2O
peptides
-
comparison of efficiency to several other proteinases
-
?
leucine-rich amylogenin peptide + H2O
leucine-rich amylogenin residues 181-186 + leucine-rich amylogenin residues 187-188
corresponds to residues 181-188 of amylogenin, recombinant enzyme, cleavage site is P186-A187
-
?
Mca-KPLGL-Dpa-AR-NH2 + H2O
?
-
-
-
?
Mca-PLA-norvaline-Dpa-AR-NH2 + H2O
?
synthetic fluorogenic substrate
-
?
Mca-PLGL-Dpa-AR-NH2 + H2O
?
Mca-PLGL-[3-DNP-2,3-DAP]-AR-NH2 + H2O
?
Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 + H2O
?
-
-
-
?
type V collagen + H2O
?
-
-
-
-
?
tyrosine-rich amylogenin peptide + H2O
tyrosine-rich amylogenin residues 36-45 + tyrosine-rich amylogenin residues 46-49
corresponds to residues 36-49 of amylogenin, recombinant enzyme, cleavage site is W45-L46
-
?
dentin sialoprotein + H2O
additional information
-
ameloblastin + H2O
?
MMP-20 processes ameloblastin during the secretory stage of amelogenesis, cleaves glycosylated recombinant porcine ameloblastin after Pro2, Gln130, Gln139, Arg170, and Ala222. MMP-20 generates the 23-kDa ameloblastin starting at Tyr223, as well as the 17-kDa (Val1-Arg170) and 15-kDa (Val1-Gln130) ameloblastin cleavage products that concentrate in the sheath space during the secretory stage
-
-
?
ameloblastin + H2O
?
cleaves glycosylated recombinant porcine ameloblastin after Pro2, Gln130, Gln139, Arg170, and Ala222. MMP-20 generates the 23-kDa ameloblastin starting at Tyr223, as well as the 17-kDa (Val1-Arg170) and 15-kDa (Val1-Gln130) ameloblastin cleavage products that concentrate in the sheath space during the secretory stage
-
-
?
ameloblastin + H2O
ameloblastin fragments
MMP-20 cleaves ameloblastin after Pro2, Gln130, Gln139, Arg170, and Ala222
fragments of 23 kDa, 17 kDa, and 15 kDa
-
?
ameloblastin + H2O
ameloblastin fragments
-
N-terminal ameloblastin cleavage products of 13, 15, and 17 kDa accumulate in the sheath space throughout the enamel layer
-
-
?
ameloblastin + H2O
ameloblastin fragments
-
MMP-20 cleaves the recombinant porcine substrate at multiple sites on the N-terminal side of the protein to fragments that show smaller bands of 7-25 kDa and larger products of 45-65 kDa. MMP-20 starts the cleavage on the N-terminal side of the protein, so that the N-terminal cleavage products are smaller than the C-terminal cleavage products digested by MMP-20 initially at one of three sitesafter Gln130. The substrate is digested by MMP-20 initially at one of three sites, after Gln130, Arg170, and Ala222, generating 6 cleavage products. These initial products are then cleaved a second or third time at these same sites, as well as at secondary sites that are located mostly near the C-terminus, after Gly300, Arg319, Ala342, and Asn31 Arg170, and Ala222, generating 6 cleavage products. These initial products are then cleaved a second or third time at these same sites, as well as at secondary sites that are located mostly near the C-terminus, after Gly300, Arg319, Ala342, and Asn31
mass spectrometry product analysis, overview
-
?
amelogenin + H2O
?
-
-
-
-
?
amelogenin + H2O
?
cleavage loci: FSY/EVL, GGW/LHH, MFP/MQP, MLP/DLT, LTL/EAW, AWP/STD
-
-
?
amelogenin + H2O
?
-
-
-
?
amelogenin + H2O
?
amelogenin with a proline 41 to threonine mutation is hydrolyzed at a lower rate by matrix metalloproteinase 20 (MMP20), resulting in an inherited tooth enamel defect, amelogenesis
-
-
?
amelogenin + H2O
?
amelogenin with a proline 41 to threonine mutation is hydrolyzed at a lower rate by matrix metalloproteinase 20 (MMP20), resulting in an inherited tooth enamel defect, amelogenesis imperfecta. P41T mutation reduces the interactions between amelogenin and MMP20, leading to decreased degradation of amelogenin by MMP20, and resulting in amelogenesis imperfecta
-
-
?
amelogenin + H2O
?
cleavage loci: FSY/EVL, GGW/LHH, MFP/MQP, MLP/DLT, DLT/LEA, LTL/EAW, AWP/STD
-
-
?
amelogenin + H2O
?
-
-
-
-
?
amelogenin + H2O
?
-
MMP-20 is involved in amelogenin processing and degradation
-
-
?
amelogenin + H2O
?
-
-
-
-
?
amelogenin + H2O
?
-
amelogenin constitutes more than 90% of enamel extracellular matrix proteins in secretory-stage enamel
-
-
?
amelogenin + H2O
?
-
most of the secreted substrate is cleaved after Ser148 to generate the 20000 Da amelogenin (Met1-Ser148), which in turn is cleaved after Trp45 to yield the tyrosine-rich amelogenin polypeptide (Met1-Trp45) and the 13000 Da amelogenin (Leu46-Ser148)
-
-
?
amelogenin + H2O
amelogenin fragments
-
-
-
-
?
amelogenin + H2O
amelogenin fragments
-
Mmp-20 cleaves amelogenin sequences after Pro162, Ser148, His62, Ala63, and Trp45. These cleavages generate all of the major cleavage products from tyrosine-rich amelogenin polypeptide that accumulate in porcine secretory stage enamel, i.e. the 23 kDa, 20 kDa, 13 kDa, 11 kDa, and 6 kDa amelogenins. And Mmp-20 cleaves leucine rich-amelogenin protein after Pro45 and Pro40, producing the two LRAP products, Mmp-20 cleavage site preferences, overview
-
-
?
amylogenin + H2O
?
-
-
-
?
amylogenin + H2O
?
involved in tooth formation
-
?
amylogenin + H2O
?
-
-
-
?
amylogenin + H2O
?
involved in tooth formation
-
?
amylogenin + H2O
?
-
recombinant substrate from pig or mouse, cleavage site determination by mass spectrometry, overview
-
?
casein + H2O
?
-
-
?
casein + H2O
?
-
zymography
-
-
?
casein + H2O
?
-
zymography
-
-
?
Mca-PLGL-Dpa-AR + H2O
?
-
-
-
-
?
Mca-PLGL-Dpa-AR + H2O
?
-
-
-
?
Mca-PLGL-Dpa-AR + H2O
?
-
-
-
?
Mca-PLGL-Dpa-AR-NH2 + H2O
?
synthetic fluorogenic substrate
-
?
Mca-PLGL-Dpa-AR-NH2 + H2O
?
-
synthetic fluorogenic substrate
-
?
Mca-PLGL-[3-DNP-2,3-DAP]-AR-NH2 + H2O
?
-
-
-
?
Mca-PLGL-[3-DNP-2,3-DAP]-AR-NH2 + H2O
?
-
-
-
?
proteins + H2O
peptides
-
-
?
proteins + H2O
peptides
-
-
-
?
proteins + H2O
peptides
-
-
?
proteins + H2O
peptides
-
-
?
proteins + H2O
peptides
-
-
?
proteins + H2O
peptides
-
-
?
proteins + H2O
peptides
-
-
-
?
proteins + H2O
peptides
-
-
?
dentin sialoprotein + H2O
additional information
-
-
multiple cleavages near the C-terminus
release of N-terminal dentin sialoprotein cleavage products ranging from 25-39 kDa
-
?
additional information
?
-
-
MMP-20 becomes functionally active when proteolytic cleavage removes the pro-domain to expose the zinc atom and free the active site for the enzyme to interact with its substrate
-
-
?
additional information
?
-
MMP-20 becomes functionally active when proteolytic cleavage removes the pro-domain to expose the zinc atom and free the active site for the enzyme to interact with its substrate
-
-
?
additional information
?
-
degradation of various components of the extracellular matrix during tooth development and pathological conditions
-
?
additional information
?
-
-
degradation of various components of the extracellular matrix during tooth development and pathological conditions
-
?
additional information
?
-
-
type III collagen can not be cleaved
-
-
?
additional information
?
-
-
MMP-20 becomes functionally active when proteolytic cleavage removes the pro-domain to expose the zinc atom and free the active site for the enzyme to interact with its substrate
-
-
?
additional information
?
-
MMP-20 becomes functionally active when proteolytic cleavage removes the pro-domain to expose the zinc atom and free the active site for the enzyme to interact with its substrate
-
-
?
additional information
?
-
-
no cleavage of dentin phosphoprotein
-
-
?
additional information
?
-
-
digestion of FRET-amelogenin peptides, labeled with 2-aminobenzoyl and 2,4-dinitrophenyl, by Mmp-20, overview
-
-
?
additional information
?
-
-
recombinant Mmp-20 is self-activated by its incubation in 4-aminophenylmercuric acetate in 10 mM CaCl2 for 24 h
-
-
?
additional information
?
-
in vitro, the formation of well-aligned bundles of enamel-like hydroxyapatite crystals is promoted in the presence of amelogenin (P173) with added MMP20, while only amorphous calcium phosphate particles are seen in the absence of MMP20. Fragment P148 has a somewhat lower capacity to stabilize amorphous calcium phosphate and prevents hydroxyapatite formation compared with P173 in the absence of MMP20, and essentially no hydroxyapatite formation is observed in the presence of somewhat higher concentrations of P148 regardless of MMP20 addition. MMP20 does not cleave fragment P148
-
-
?
additional information
?
-
-
in vitro, the formation of well-aligned bundles of enamel-like hydroxyapatite crystals is promoted in the presence of amelogenin (P173) with added MMP20, while only amorphous calcium phosphate particles are seen in the absence of MMP20. Fragment P148 has a somewhat lower capacity to stabilize amorphous calcium phosphate and prevents hydroxyapatite formation compared with P173 in the absence of MMP20, and essentially no hydroxyapatite formation is observed in the presence of somewhat higher concentrations of P148 regardless of MMP20 addition. MMP20 does not cleave fragment P148
-
-
?
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Adenocarcinoma
High-Level Expression and Prognostic Significance of Matrix Metalloprotease-19 and Matrix Metalloprotease-20 in Human Pancreatic Ductal Adenocarcinoma.
Adenocarcinoma
Lung development, repair and cancer: A study on the role of MMP20 gene in adenocarcinoma.
Adenocarcinoma of Lung
Lung development, repair and cancer: A study on the role of MMP20 gene in adenocarcinoma.
Ameloblastoma
Immunohistochemical detection and distribution of enamelysin (MMP-20) in human odontogenic tumors.
Ameloblastoma
Immunohistochemical expression of WNT5A and MMPs in odontogenic epithelial tumors and cysts.
Amelogenesis Imperfecta
A developmental comparison of matrix metalloproteinase-20 and amelogenin null mouse enamel.
Amelogenesis Imperfecta
A multidisciplinary approach for the diagnosis of hypocalcified amelogenesis imperfecta in two Chilean families.
Amelogenesis Imperfecta
Abrogation of epithelial BMP2 and BMP4 causes Amelogenesis Imperfecta by reducing MMP20 and KLK4 expression.
Amelogenesis Imperfecta
Amelogenesis imperfecta: an introduction.
Amelogenesis Imperfecta
Amelogenin processing by MMP-20 prevents protein occlusion inside calcite crystals.
Amelogenesis Imperfecta
Analyses of MMP20 Missense Mutations in Two Families with Hypomaturation Amelogenesis Imperfecta.
Amelogenesis Imperfecta
Dental malformations associated with biallelic MMP20 mutations.
Amelogenesis Imperfecta
Developmental biology and genetics of dental malformations.
Amelogenesis Imperfecta
Enamelysin (matrix metalloproteinase 20)-deficient mice display an amelogenesis imperfecta phenotype.
Amelogenesis Imperfecta
Evolutionary Analysis Predicts Sensitive Positions of MMP20 and Validates Newly- and Previously-Identified MMP20 Mutations Causing Amelogenesis Imperfecta.
Amelogenesis Imperfecta
Functions of KLK4 and MMP-20 in dental enamel formation.
Amelogenesis Imperfecta
Homozygous and compound heterozygous MMP20 mutations in amelogenesis imperfecta.
Amelogenesis Imperfecta
Human and mouse enamel phenotypes resulting from mutation or altered expression of AMEL, ENAM, MMP20 and KLK4.
Amelogenesis Imperfecta
M180 Amelogenin Processed by MMP20 is Sufficient for Decussating Murine Enamel.
Amelogenesis Imperfecta
Matrix metalloproteinase 20 promotes a smooth enamel surface, a strong dentino-enamel junction, and a decussating enamel rod pattern.
Amelogenesis Imperfecta
MMP-20 mutation in autosomal recessive pigmented hypomaturation amelogenesis imperfecta.
Amelogenesis Imperfecta
MMP20 active-site mutation in hypomaturation amelogenesis imperfecta.
Amelogenesis Imperfecta
MMP20 Cleaves E-Cadherin and Influences Ameloblast Development.
Amelogenesis Imperfecta
MMP20 hemopexin domain mutation in amelogenesis imperfecta.
Amelogenesis Imperfecta
MMP20 Modulates Cadherin Expression in Ameloblasts as Enamel Develops.
Amelogenesis Imperfecta
MMP20, KLK4, and MMP20/KLK4 double null mice define roles for matrix proteases during dental enamel formation.
Amelogenesis Imperfecta
Novel MMP20 and KLK4 Mutations in Amelogenesis Imperfecta.
Amelogenesis Imperfecta
Novel WDR72 Mutation and Cytoplasmic Localization.
Amelogenesis Imperfecta
Premature stop codon in MMP20 causing amelogenesis imperfecta.
Amelogenesis Imperfecta
Protocol GenoDENT: Implementation of a New NGS Panel for Molecular Diagnosis of Genetic Disorders with Orodental Involvement.
Amelogenesis Imperfecta
Reduced amelogenin-MMP20 interactions in amelogenesis imperfecta.
Amelogenesis Imperfecta
Shear bond strength of dentin and deproteinized enamel of amelogenesis imperfecta mouse incisors.
Amelogenesis Imperfecta
Spectrum of pathogenic variants and founder effects in amelogenesis imperfecta associated with MMP20.
Amelogenesis Imperfecta
X-linked amelogenesis imperfecta may result from decreased formation of tyrosine rich amelogenin peptide (TRAP).
Breast Neoplasms
Additional MDA-MB-231 breast cancer cell matrix metalloproteinases promote invasiveness.
Carcinogenesis
Survey of dentin sialophosphoprotein and its cognate matrix metalloproteinase-20 in human cancers.
Carcinoma
Effects of DSPP and MMP20 Silencing on Adhesion, Metastasis, Angiogenesis, and Epithelial-Mesenchymal Transition Proteins in Oral Squamous Cell Carcinoma Cells.
Carcinoma
Expression and regulation of MMP-20 in human tongue carcinoma cells.
Carcinoma
Expression of Matrix Metalloproteinase (MMP)-20 and Potential Interaction with Dentin Sialophosphoprotein (DSPP) in Human Major Salivary Glands.
Carcinoma
Ghost cells in calcifying odontogenic cyst express enamel-related proteins.
Carcinoma
High-Level Expression and Prognostic Significance of Matrix Metalloprotease-19 and Matrix Metalloprotease-20 in Human Pancreatic Ductal Adenocarcinoma.
Carcinoma
Matrix Metalloproteinase 20-Dentin Sialophosphoprotein Interaction in Oral Cancer.
Carcinoma
Prognostic significance of matrix metalloproteinase-20 overexpression in laryngeal squamous cell carcinoma.
Carcinoma
Survey of dentin sialophosphoprotein and its cognate matrix metalloproteinase-20 in human cancers.
Choroidal Neovascularization
MMP20 and ARMS2/HTRA1 Are Associated with Neovascular Lesion Size in Age-Related Macular Degeneration.
Cysts
Immunohistochemical expression of WNT5A and MMPs in odontogenic epithelial tumors and cysts.
Dental Caries
Association of genetic variants in enamel-formation genes with dental caries: A meta- and gene-cluster analysis.
Dental Caries
Chosen single nucleotide polymorphisms (SNPs) of enamel formation genes and dental caries in a population of Polish children.
Dental Caries
Matrix metalloproteinases gene variants and dental caries in Czech children.
Dental Caries
MMP20 rs1784418 Protects Certain Populations against Caries.
Dental Caries
Postradiation Matrix Metalloproteinase-20 Expression and Its Impact on Dental Micromorphology and Radiation-Related Caries.
Dental Caries
The localization of matrix metalloproteinase-20 (MMP-20, enamelysin) in mature human teeth.
Dentin Dysplasia
Developmental biology and genetics of dental malformations.
Dentinogenesis Imperfecta
Developmental biology and genetics of dental malformations.
Endometrial Neoplasms
[High expression of MMP20 may be a potential prognostic factor for poor outcomes of patients with endometrial carcinoma].
Fluorosis, Dental
Assessment of Dental Fluorosis in Mmp20+/- Mice.
Fluorosis, Dental
DNA sequencing reveals AMELX, ODAM and MMP20 variations in dental fluorosis.
Fluorosis, Dental
Evaluation of genetic polymorphisms in MMP2, MMP9 and MMP20 in Brazilian children with dental fluorosis.
Lymphatic Metastasis
Prognostic significance of matrix metalloproteinase-20 overexpression in laryngeal squamous cell carcinoma.
Macular Degeneration
MMP20 and ARMS2/HTRA1 Are Associated with Neovascular Lesion Size in Age-Related Macular Degeneration.
Mouth Neoplasms
Effects of DSPP and MMP20 Silencing on Adhesion, Metastasis, Angiogenesis, and Epithelial-Mesenchymal Transition Proteins in Oral Squamous Cell Carcinoma Cells.
Myocardial Infarction
[The Association of Gene Polymorphisms of Matrix Metalloproteinases (-9, -12 and -20) and Collagen Type I Degradation Products With the Remodeling of the Left Ventricle in Patients With Acute Myocardial Infarction].
Neoplasm Metastasis
Effects of DSPP and MMP20 Silencing on Adhesion, Metastasis, Angiogenesis, and Epithelial-Mesenchymal Transition Proteins in Oral Squamous Cell Carcinoma Cells.
Neoplasm Metastasis
Prognostic significance of matrix metalloproteinase-20 overexpression in laryngeal squamous cell carcinoma.
Neoplasms
Deciphering the genetic alterations in matrix metallo-proteinase gene family and its putative association with head and neck squamous cell carcinoma.
Neoplasms
Expression of collagen XVIII and MMP-20 in developing teeth and odontogenic tumors.
Neoplasms
Expression Pattern of Matrix Metalloproteinase 20 (MMP20) in Human Tumors.
Neoplasms
High-Level Expression and Prognostic Significance of Matrix Metalloprotease-19 and Matrix Metalloprotease-20 in Human Pancreatic Ductal Adenocarcinoma.
Neoplasms
Immunohistochemical detection and distribution of enamelysin (MMP-20) in human odontogenic tumors.
Neoplasms
Immunohistochemical expression of WNT5A and MMPs in odontogenic epithelial tumors and cysts.
Neoplasms
Kallikrein 4 and matrix metalloproteinase-20 immunoexpression in malignant, benign and infiltrative odontogenic tumors.
Neoplasms
Lung development, repair and cancer: A study on the role of MMP20 gene in adenocarcinoma.
Neoplasms
mRNA expression and phenotype of odontogenic tumours in the v-Ha-ras transgenic mouse.
Neoplasms
One-step sandwich enzyme immunoassay using monoclonal antibodies for detection of human enamelysin (MMP-20).
Neoplasms
Prognostic significance of matrix metalloproteinase-20 overexpression in laryngeal squamous cell carcinoma.
Neoplasms
Survey of dentin sialophosphoprotein and its cognate matrix metalloproteinase-20 in human cancers.
Neuroblastoma
Common variants in MMP20 at 11q22.2 predispose to 11q deletion and neuroblastoma risk.
Odontogenic Cyst, Calcifying
Ghost cells in calcifying odontogenic cyst express enamel-related proteins.
Odontogenic Cyst, Calcifying
Immunohistochemical detection and distribution of enamelysin (MMP-20) in human odontogenic tumors.
Odontogenic Tumors
Expression and regulation of MMP-20 in human tongue carcinoma cells.
Odontogenic Tumors
Expression of collagen XVIII and MMP-20 in developing teeth and odontogenic tumors.
Odontogenic Tumors
Immunohistochemical detection and distribution of enamelysin (MMP-20) in human odontogenic tumors.
Odontogenic Tumors
Immunohistochemical expression of WNT5A and MMPs in odontogenic epithelial tumors and cysts.
Odontogenic Tumors
Kallikrein 4 and matrix metalloproteinase-20 immunoexpression in malignant, benign and infiltrative odontogenic tumors.
Odontoma
Immunohistochemical detection and distribution of enamelysin (MMP-20) in human odontogenic tumors.
Osteonecrosis
MMP20 Single-Nucleotide Polymorphisms Correlate with Susceptibility to Alcohol-Induced Osteonecrosis of the Femoral Head in Chinese Males.
Ovarian Neoplasms
Association between matrix metalloproteinases polymorphisms and ovarian cancer risk: A meta-analysis and systematic review.
Squamous Cell Carcinoma of Head and Neck
Deciphering the genetic alterations in matrix metallo-proteinase gene family and its putative association with head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Effects of DSPP and MMP20 Silencing on Adhesion, Metastasis, Angiogenesis, and Epithelial-Mesenchymal Transition Proteins in Oral Squamous Cell Carcinoma Cells.
Squamous Cell Carcinoma of Head and Neck
Expression of Matrix Metalloproteinase (MMP)-20 and Potential Interaction with Dentin Sialophosphoprotein (DSPP) in Human Major Salivary Glands.
Squamous Cell Carcinoma of Head and Neck
Matrix Metalloproteinase 20-Dentin Sialophosphoprotein Interaction in Oral Cancer.
Squamous Cell Carcinoma of Head and Neck
Prognostic significance of matrix metalloproteinase-20 overexpression in laryngeal squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Survey of dentin sialophosphoprotein and its cognate matrix metalloproteinase-20 in human cancers.
Thyroid Neoplasms
Survey of dentin sialophosphoprotein and its cognate matrix metalloproteinase-20 in human cancers.
Uterine Cervical Neoplasms
Survey of dentin sialophosphoprotein and its cognate matrix metalloproteinase-20 in human cancers.
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Boeckmann, B.; Bairoch, A.; Apweiler, R.; Blatter, M.C.; Estreicher, A.; Gasteiger, E.; Martin M.J.; Michoud, K.; O'Donovan, C.; Phan, I.; Pilbout, S.; Schneider, M.
The SWISS-PROT protein knowledgebase and its supplement TrEMBL
Nucleic Acids Res.
31
365-370
2003
Mus musculus (P57748), Sus scrofa (P79287)
brenda
Llano, E.; Pendas, A.M.; Knauper, V.; Sorsa, T.; Salo, T.; Salido, E.; Murphy, G.; Simmer, J.P.; Bartlett, J.D.; Lopez-Otin, C.
Identification and structural and functional characterization of human enamelysin (MMP-20)
Biochemistry
36
15101-15108
1997
Homo sapiens (O60882), Homo sapiens
brenda
Li, W.; Machule, D.; Gao, C.; DenBesten, P.K.
Activation of recombinant bovine matrix metalloproteinase-20 and its hydrolysis of two amelogenin oligopeptides
Eur. J. Oral Sci.
107
352-359
1999
Bos taurus (O18767), Bos taurus
brenda
Stracke, J.O.; Fosang, A.J.; Last, K.; Mercuri, F.A.; Pendas, A.M.; Llano, E.; Perris, R.; Di Cesare, P.E.; Murphy, G.; Knauper, V.
Matrix metalloproteinases 19 and 20 cleave aggrecan and cartilage oligomeric matrix protein (COMP)
FEBS Lett.
478
52-56
2000
Homo sapiens (O60882), Homo sapiens
brenda
Ferreras, M.; Felbor, U.; Lenhard, T.; Olsen, B.R.; Delaisse, J.M.
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