Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
amelogenin + H2O | Mus musculus | - |
? | - |
? | |
E-cadherin + H2O | Sus scrofa | MMP20 cleaves the extracellular domain of E-cadherin | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Sus scrofa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
Q-Sepharose column chromatography and heparin Sepharose 6 column chromatography | Mus musculus |
Q-Sepharose column chromatography and heparin Sepharose 6 column chromatography | Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
ameloblast | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
amelogenin + H2O | - |
Mus musculus | ? | - |
? | |
E-cadherin + H2O | MMP20 cleaves the extracellular domain of E-cadherin | Sus scrofa | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MMP20 | - |
Mus musculus |
MMP20 | - |
Sus scrofa |
General Information | Comment | Organism |
---|---|---|
malfunction | Mmp20-deficient mouse ameloblasts can initiate, terminate, and reinitiate the secretory stage of enamel development | Mus musculus |
physiological function | MMP20 is required for proper enamel formation. MMP20 influences ameloblast developmental progression through hydrolysis of cadherin extracellular domains with associated release of transcription factor(s) | Mus musculus |
physiological function | MMP20 is required for proper enamel formation. MMP20 influences ameloblast developmental progression through hydrolysis of cadherin extracellular domains with associated release of transcription factor(s) | Sus scrofa |