Protein Variants | Comment | Organism |
---|---|---|
G115A | slightly reduced activity | Pseudomonas aeruginosa |
H94A | mutation is moderately unstable and allows the production of a LasA protein with low enzymatic activity | Pseudomonas aeruginosa |
I101A | mutation is moderately unstable and allows the production of a LasA protein with low enzymatic activity | Pseudomonas aeruginosa |
L92A | mutation results in highly unstable protein that is susceptible to proteolytic degradation | Pseudomonas aeruginosa |
N102A | mutation is moderately unstable and allows the production of a LasA protein with low enzymatic activity | Pseudomonas aeruginosa |
W95A | mutation results in highly unstable protein that is susceptible to proteolytic degradation | Pseudomonas aeruginosa |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
20000 | - |
mature enzyme, SDS-PAGE | Pseudomonas aeruginosa |
42000 | - |
SDS-PAGE, LasA is synthesized as a preproenzyme that undergoes proteolysis to remove a 22000 Da amino-terminal propeptide | Pseudomonas aeruginosa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas aeruginosa | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | staphylolytic activity is pentaglycine in the peptidoglycan of Staphylococcus aureus | Pseudomonas aeruginosa | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
LasA endopeptidase | - |
Pseudomonas aeruginosa |