Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Cys-Gln-Val | tripeptide Cys-Gln-Val shows about 50%, 30% and 25% residual activity at 0.0005, 0.00005 and 0.000005 mM, respectively | Homo sapiens | |
Gln-Cys-Ala | tripeptide Gln-Cys-Ala shows about 35%, 20% and 22% residual activity at 0.0005, 0.00005 and 0.000005 mM, respectively | Homo sapiens | |
Gln-Cys-Val | tripeptide Gln-Cys-Val shows about 45%, 28% and 10% residual activity at 0.0005, 0.00005 and 0.000005 mM, respectively | Homo sapiens | |
Gln-Val-Cys | tripeptide Gln-Val-Cys shows about 59%, 40% and 8% residual activity at 0.0005, 0.00005 and 0.000005 mM, respectively | Homo sapiens | |
additional information | the enzyme is not inhibited by 0.005 mM glutathione | Homo sapiens | |
TAPI-1 | TAPI-1 inhibits 19% and 45% of enzyme activity at 0.0001 and 0.0001 mM, respectively | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | required | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Mca-PLAQAVDpa-RSSSR-NH2 + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
a disintegrin and metalloproteinase 17 | - |
Homo sapiens |
ADAM17 | - |
Homo sapiens |
TACE | - |
Homo sapiens |
TNF-alpha converting enzyme | - |
Homo sapiens |
tumour necrosis factor-alpha converting enzyme | - |
Homo sapiens |