Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.24.86 extracted from

  • Bostanci, N.; Reddi, D.; Rangarajan, M.; Curtis, M.A.; Belibasakis, G.N.
    Porphyromonas gingivalis stimulates TACE production by T cells (2009), Oral Microbiol. Immunol., 24, 146-151.
    View publication on PubMed
Search for more literature for 3.4.24.86

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
JURKAT cell
-
 Homo sapiens
-

Expression

Organism Comment Expression
Homo sapiens Porphyromonas gingivalis challenge results in a concentration-dependent enhancement of TACE messenger RNA expression and protein release by Jurkat cells. TLCK treatment or heat treatment of Porphyromonas gingivalis culture supernatants decreases TACE release to control levels up

General Information

General Information Comment Organism
physiological function Porphyromonas gingivalis challenge results in a concentration-dependent enhancement of TACE messenger RNA expression and protein release by Jurkat cells. The induction of TACE by T-cells in response to Porphyromonas gingivalis may in turn favour the shedding of host cell-bound cytokines into the local microenvironment, potentially amplifying the inflammatory response Homo sapiens