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Literature summary for 3.4.24.86 extracted from
- ADAM17 activity during human neutrophil activation and apoptosis (2006), Eur. J. Immunol., 36, 968-976.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| N-formyl-L-methionyl-phenylalanine | ADAM17 substrates undergo efficient turnover during extended neutrophil activation by N-formyl-L-methionyl-phenylalanine | Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| neutrophil | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-selectin + H2O | - |
Homo sapiens | ? | - |
? | |
| p75 tumour necrosis factor receptor + H2O | - |
Homo sapiens | ? | - |
? | |
| proTNF-alpha + H2O | - |
Homo sapiens | soluble TNF-alpha | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ADAM17 | - |
Homo sapiens |
| TACE | - |
Homo sapiens |
| TNF-alpha converting enzyme | - |
Homo sapiens |
| tumor necrosis factor alpha-converting enzyme | - |
Homo sapiens |
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