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Literature summary for 3.4.24.69 extracted from

  • Moritz, M.S.; Tepp, W.H.; Bradshaw, M.; Johnson, E.A.; Pellett, S.
    Isolation and characterization of the novel botulinum neurotoxin A subtype 6 (2018), mSphere, 3, e00466-18 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.24.69

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ the enzyme is a zinc metalloprotease Clostridium botulinum

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
150000
-
 gel filtration Clostridium botulinum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
synaptosome-associated protein SNAP-25 + H2O Clostridium botulinum
-
 ?
-
 ?
synaptosome-associated protein SNAP-25 + H2O Clostridium botulinum CDC41370
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Clostridium botulinum
-
-
-
Clostridium botulinum CDC41370
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information subtype BoNT/A6 enters cells more efficiently than other enzyme subtypes Clostridium botulinum ?
-
 ?
additional information subtype BoNT/A6 enters cells more efficiently than other enzyme subtypes Clostridium botulinum CDC41370 ?
-
 ?
synaptosome-associated protein SNAP-25 + H2O
-
 Clostridium botulinum ?
-
 ?
synaptosome-associated protein SNAP-25 + H2O
-
 Clostridium botulinum CDC41370 ?
-
 ?

Synonyms

Synonyms Comment Organism
BoNT/A1
-
 Clostridium botulinum
BoNT/A6
-
 Clostridium botulinum
botulinum neurotoxin A subtype 1
-
 Clostridium botulinum
botulinum neurotoxin A subtype 6
-
 Clostridium botulinum