Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
heparin-binding epidermal growth factor-like growth factor + H2O | Homo sapiens | substrate is synthesized as a transmembrane protein. Enzyme enhances ectodomain shedding of substrate in coperation with tumor necrosis factor-alpha-converting enzyme. Metalloendopeptidase activity of enzyme is not required for enhancement of shedding | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O43847 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
heparin-binding epidermal growth factor-like growth factor + H2O | substrate is synthesized as a transmembrane protein. Enzyme enhances ectodomain shedding of substrate in coperation with tumor necrosis factor-alpha-converting enzyme. Metalloendopeptidase activity of enzyme is not required for enhancement of shedding | Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | interaction of enzyme with tumor necrosis factor-alpha-converting enzyme | Homo sapiens |