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Literature summary for 3.4.24.11 extracted from
- Increased pain and neurogenic inflammation in mice deficient of neutral endopeptidase (2008), Neurobiol. Dis., 35, 177-183.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | after chronic constriction injury of the right sciatic nerve, neprilysin knock-out mice are more sensitive to heat, to mechanical stimuli, and to cold than wild type mice. Tissue injury without nerve injury produced no differences between genotypes. After chronic constriction injury, neprilysin knock-out mice show increased hind paw edema but lower skin temperatures than wild type mice. Substance P and endothelin 1 are increased in sciatic nerves. Tissue calcitonin gene related peptide content does not differ between the genotypes | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
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Release 2023.1 (January 2023)
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