Literature summary for 3.4.23.B11 extracted from

Moschall, R.; Denk, S.; Erkelenz, S.; Schenk, C.; Schaal, H.; Bodem, J.
A purine-rich element in foamy virus pol regulates env splicing and gag/pol expression (2017), Retrovirology, 14, 10 .

Search for more literature for 3.4.23.B11

Cloned(Commentary)

Cloned (Comment)	Organism
gene pol encoding the Pro-Pol polyprotein which includes the enzyme subunits, expression regulation and splicing, overview. The foamy viral purine-rich C element, also encoded by gene pol, regulates splicing by suppressing the branch point recognition of the strongest env splice acceptor. It is essential for the formation of unspliced gag and singly spliced pol transcripts	human foamy virus

Organism

Organism	UniProt	Comment	Textmining
human foamy virus	P14350	Pro-Pol polyprotein; i.e. Human spumaretrovirus	-

Subunits

Subunits	Comment	Organism
dimer	the foamy viral genome encodes four central purine-rich elements localized in the integrase-coding region of pol, which encodes th Pro-Pol polyprotein. The first two of these RNA elements (A and B) are required for protease dimerization and activation	human foamy virus

Synonyms

Synonyms	Comment	Organism
human foamy virus protease	-	human foamy virus

General Information

General Information	Comment	Organism
additional information	the Pro-Pol polyprotein elements A and B are required for protease dimerization and activation, while the C-element is required for pol expression and splicing regulation	human foamy virus

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Release 2023.1 (January 2023)