Inhibitors | Comment | Organism | Structure |
---|---|---|---|
pepstatin A | - |
Homo sapiens | |
pepstatin A | - |
Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.022 | - |
POMC (165-174) | in 0.2 M sodium formate buffer, pH 4.0, at 37°C | Sus scrofa | |
0.029 | - |
POMC (165-174) | in 0.2 M sodium formate buffer, pH 4.0, at 37°C | Homo sapiens | |
0.079 | - |
AFPLEFIREL | in 0.2 M sodium formate buffer, pH 4.0, at 37°C | Homo sapiens | |
0.084 | - |
AFPLEFFREL | in 0.2 M sodium formate buffer, pH 4.0, at 37°C | Homo sapiens | |
0.098 | - |
AFPLEFIREL | in 0.2 M sodium formate buffer, pH 4.0, at 37°C | Sus scrofa | |
0.17 | - |
AFPLEFFREL | in 0.2 M sodium formate buffer, pH 4.0, at 37°C | Sus scrofa | |
0.3 | - |
AFPLEFEREL | in 0.2 M sodium formate buffer, pH 4.0, at 37°C | Homo sapiens | |
0.4 | - |
AFPLEFEREL | in 0.2 M sodium formate buffer, pH 4.0, at 37°C | Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Sus scrofa | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
AFPLEFEREL + H2O | - |
Homo sapiens | AFPLEF + EREL | - |
? | |
AFPLEFEREL + H2O | - |
Sus scrofa | AFPLEF + EREL | - |
? | |
AFPLEFFREL + H2O | - |
Homo sapiens | AFPLEF + FREL | - |
? | |
AFPLEFFREL + H2O | - |
Sus scrofa | AFPLEF + FREL | - |
? | |
AFPLEFIREL + H2O | - |
Homo sapiens | AFPLEF + IREL | - |
? | |
AFPLEFIREL + H2O | - |
Sus scrofa | AFPLEF + IREL | - |
? | |
dynorphin A (1-7) + H2O | - |
Homo sapiens | ? | - |
? | |
dynorphin A (1-7) + H2O | - |
Sus scrofa | ? | - |
? | |
Hemoglobin + H2O | - |
Homo sapiens | ? | - |
? | |
Hemoglobin + H2O | - |
Sus scrofa | ? | - |
? | |
HPHLSFMAI + H2O | best substrate | Homo sapiens | HPHLSF + Met-Ala-Ile + ? | - |
? | |
HPHLSFMAI + H2O | best substrate | Sus scrofa | HPHLSF + Met-Ala-Ile + ? | - |
? | |
KPAEFFRL + H2O | - |
Homo sapiens | KPAEF + FRL | - |
? | |
KPAEFFRL + H2O | - |
Sus scrofa | KPAEF + FRL | - |
? | |
KYSSWYVAL + H2O | - |
Homo sapiens | KYSSW + YVAL | - |
? | |
KYSSWYVAL + H2O | - |
Sus scrofa | KYSSW + YVAL | - |
? | |
additional information | pepsin A strongly prefers a hydrophobic/aromatic residue at P1 in any type of peptide | Homo sapiens | ? | - |
? | |
additional information | pepsin A strongly prefers a hydrophobic/aromatic residue at P1 in any type of peptide | Sus scrofa | ? | - |
? | |
NT/NMN (142-151) + H2O | - |
Homo sapiens | KIPYIL + KRQL | - |
? | |
NT/NMN (142-151) + H2O | - |
Sus scrofa | KIPYIL + KRQL | - |
? | |
POMC (165-174) + H2O | - |
Homo sapiens | AFPLE + FKREL | - |
? | |
POMC (165-174) + H2O | - |
Sus scrofa | AFPLE + FKREL | - |
? | |
substance P + H2O | - |
Homo sapiens | RPKPQQF + FGLM | - |
? | |
substance P + H2O | - |
Sus scrofa | RPKPQQF + FGLM | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
2.7 | - |
POMC (165-174) | in 0.2 M sodium formate buffer, pH 4.0, at 37°C | Homo sapiens | |
3.7 | - |
POMC (165-174) | in 0.2 M sodium formate buffer, pH 4.0, at 37°C | Sus scrofa | |
8.9 | - |
AFPLEFEREL | in 0.2 M sodium formate buffer, pH 4.0, at 37°C | Homo sapiens | |
45 | - |
AFPLEFEREL | in 0.2 M sodium formate buffer, pH 4.0, at 37°C | Sus scrofa | |
56 | - |
AFPLEFIREL | in 0.2 M sodium formate buffer, pH 4.0, at 37°C | Homo sapiens | |
85 | - |
AFPLEFFREL | in 0.2 M sodium formate buffer, pH 4.0, at 37°C | Homo sapiens | |
203 | - |
AFPLEFIREL | in 0.2 M sodium formate buffer, pH 4.0, at 37°C | Sus scrofa | |
472 | - |
AFPLEFFREL | in 0.2 M sodium formate buffer, pH 4.0, at 37°C | Sus scrofa |
kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
29 | - |
AFPLEFEREL | in 0.2 M sodium formate buffer, pH 4.0, at 37°C | Homo sapiens | |
93 | - |
POMC (165-174) | in 0.2 M sodium formate buffer, pH 4.0, at 37°C | Homo sapiens | |
110 | - |
AFPLEFEREL | in 0.2 M sodium formate buffer, pH 4.0, at 37°C | Sus scrofa | |
170 | - |
POMC (165-174) | in 0.2 M sodium formate buffer, pH 4.0, at 37°C | Sus scrofa | |
730 | - |
AFPLEFIREL | in 0.2 M sodium formate buffer, pH 4.0, at 37°C | Homo sapiens | |
1000 | - |
AFPLEFFREL | in 0.2 M sodium formate buffer, pH 4.0, at 37°C | Homo sapiens | |
2100 | - |
AFPLEFIREL | in 0.2 M sodium formate buffer, pH 4.0, at 37°C | Sus scrofa | |
2800 | - |
AFPLEFFREL | in 0.2 M sodium formate buffer, pH 4.0, at 37°C | Sus scrofa |