Literature summary for 3.4.22.B73 extracted from

Federzoni, E.A.; Gloor, S.; Jin, J.; Shan-Krauer, D.; Fey, M.F.; Torbett, B.E.; Tschan, M.P.
Linking the SUMO protease SENP5 to neutrophil differentiation of AML cells (2015), Leuk. Res. Rep., 4, 32-35 .

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Application

Application	Comment	Organism
medicine	Senp5 is significantly repressed in clinical acute myeloid leukemia when compared to healthy neutrophil samples	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q96HI0	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
neutrophil	-	Homo sapiens	-

General Information

General Information	Comment	Organism
physiological function	Senp5 is significantly repressed in clinical acute myeloid leukemia when compared to healthy neutrophil samples. SENP5 expression is induced during neutrophil differentiation of acute myeloid leukemia cells, and knocking down SENP5 results in significantly attenuated neutrophil differentiation	Homo sapiens

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Release 2023.1 (January 2023)