Organism | UniProt | Comment | Textmining |
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Saccharomyces cerevisiae | - |
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General Information | Comment | Organism |
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physiological function | loss of Upl2 results in ChrI disomy, which is eliminated by extended passaging. The mRNA levels for almost all ribosomal proteins increase transiently upon initial loss of Ulp2, but elevated Ccr4 deadenylase levels limit excess ribosome formation. Extended passaging leads to increased levels of many small nucleolar RNAs involved in ribosome biogenesis, and higher dosage of three linked ChrXII small nucleolar RNA genes suppress ChrXII disomy in Ulp2 mutant cells | Saccharomyces cerevisiae |