Literature summary for 3.4.22.B67 extracted from

Ryu, H.Y.; Su, D.; Wilson-Eisele, N.R.; Zhao, D.; Lopez-Giraldez, F.; Hochstrasser, M.
The Ulp2 SUMO protease promotes transcription elongation through regulation of histone sumoylation (2019), EMBO J., 38, e102003 .

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Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
nucleus	-	Saccharomyces cerevisiae	5634	-

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	-	-	-

General Information

General Information	Comment	Organism
physiological function	Ulp2 is recruited to transcriptionally active genes to control local polysumoylation. Mutant Ulp2 cells show impaired association of RNA polymerase II with, and diminished expression of, constitutively active genes and the inducible CUP1 gene. Ulp2 loss sensitizes cells to 6-azauracil, a hallmark of transcriptional elongation defects	Saccharomyces cerevisiae

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Release 2023.1 (January 2023)