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Literature summary for 3.4.22.B67 extracted from

  • Kroetz, M.B.; Su, D.; Hochstrasser, M.
    Essential role of nuclear localization for yeast Ulp2 SUMO protease function (2009), Mol. Biol. Cell, 20, 2196-2206.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.22.B67

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus the N-terminal domain is essential for Ulp2 function and is required for nuclear targeting Saccharomyces cerevisiae 5634
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Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae P40537
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
polySUMO-protein conjugate + H2O Ulp2 can cleave the SUMO-SUMO linkage in poly-SUMO chains. The C-terminal noncatalytic domain of Ulp2 is required for efficient depolymerization of large poly-SUMO conjugates in vivo Saccharomyces cerevisiae SUMO + truncated polySUMO-protein conjugate + H2O
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General Information

General Information Comment Organism
physiological function Ulp2 is a nuclear protein required for chromosome stability and cell cycle restart after checkpoint arrest Saccharomyces cerevisiae