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Literature summary for 3.4.22.B24 extracted from

  • Zhang, F.; Wang, Q.; Ye, L.; Feng, Y.; Zhang, X.
    Hepatitis B virus X protein upregulates expression of calpain small subunit 1 via nuclear factor-kappaB/p65 in hepatoma cells (2010), J. Med. Virol., 82, 920-928.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Hep-G2 cell
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Homo sapiens
-

Synonyms

Synonyms Comment Organism
calpain small subunit 1 both of micro- and m-calpains are heterodimers, consisting of a distinct large 80000 Da catalytic subunit and a common small 28000 Da regulatory subunit termed Capn4 Homo sapiens
Capn4
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Homo sapiens

Expression

Organism Comment Expression
Homo sapiens HBx is able to upregulate the expression of Capn4 in human hepatoma HepG2 (or H7402) cells up

General Information

General Information Comment Organism
physiological function Capn4 as a regulatory subunit is essential for micro- and m-calpain activity, the upregulation of Capn4 mediated by HBx contributes to migration of hepatoma cells Homo sapiens