Protein Variants | Comment | Organism |
---|---|---|
additional information | CTSV knockdown by RNAi | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O60911 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cardiomyocyte | - |
Homo sapiens | - |
HCM cell | - |
Homo sapiens | - |
heart | - |
Homo sapiens | - |
myocardium | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
CTSV | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | exogenous cathepsin V protein protects human cardiomyocytes from angiotensin II-induced hypertrophy, human cardiomyocytes hypertrophic cardiomyopathy (HCM) as a cell model to investigate the effects of exogenous CTSV on Ang II-induced cardiac cell hypertrophy, overview. Analysis of the mechanism of CTSV cardioprotection, overview. Exogenous CTSV inhibits Ang II-induced hypertrophy in HCM cells by inhibiting PI3K/Akt/mTOR | Homo sapiens |