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Literature summary for 3.4.21.B5 extracted from

  • Stevens, R.L.; McNeil, H.P.; Wensing, L.A.; Shin, K.; Wong, G.W.; Hansbro, P.M.; Krilis, S.A.
    Experimental arthritis is dependent on mouse mast cell protease-5 (2017), J. Biol. Chem., 292, 5392-5404 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.B5

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Fibronectin + H2O Mus musculus
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus P21844
-
-

Source Tissue

Source Tissue Comment Organism Textmining
mast cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Fibronectin + H2O
-
 Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
mast cell protease-5
-
 Mus musculus
MCP-5
-
 Mus musculus

General Information

General Information Comment Organism
malfunction experimental arthritis is markedly reduced in enzyme-deficient mice relative to wild type mice Mus musculus
metabolism the enzyme is needed to target translated mast cell carboxypeptidase A to the secretory granule along with heparin-containing serglycin proteoglycans. Alternately, the enzyme is needed to protect mast cell carboxypeptidase A from autolysis in the cell's granules Mus musculus