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Literature summary for 3.4.21.71 extracted from

  • Di Cerbo, A.; Laurino, C.; Palmieri, B.; Iannitti, T.
    A dietary supplement improves facial photoaging and skin sebum, hydration and tonicity modulating serum fibronectin, neutrophil elastase 2, hyaluronic acid and carbonylated proteins (2015), J. Photochem. Photobiol. B, 144C, 94-103.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
collagen fiber + H2O Homo sapiens
-
 ?
-
 ?
elastic fiber + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
neutrophil
-
 Homo sapiens
-
serum
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
collagen fiber + H2O
-
 Homo sapiens ?
-
 ?
elastic fiber + H2O
-
 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
neutrophil elastase 2
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens serum neutrophil elastase 2 concentration is significantly decreased in patients treated with the dietary supplement down
Homo sapiens serum elastase 2 concentration was higher in patients affected by photoaging if compared with healthy controls compared with subjects receiving placebo 2 weeks after the end of treatment up

General Information

General Information Comment Organism
physiological function the enzyme's biological functions include involvement in migration of neutrophils by means of focal proteolysis, killing of microorganisms, and degradation/activation of various proteins including cytokines, chemokines and ECM proteins Homo sapiens